63916-73-4 Usage
Description
(4aS,8aS)-8-(benzoyloxy)-2-methyldecahydroisoquinolinium chloride is a quaternary ammonium salt derived from isoquinoline, a heterocyclic compound. It features a 2-methyldecahydroisoquinolinium cation with a benzoyloxy group and a chloride anion, known for its potential pharmacological properties, including antimicrobial and antiviral activities.
Uses
Used in Pharmaceutical Synthesis:
(4aS,8aS)-8-(benzoyloxy)-2-methyldecahydroisoquinolinium chloride is used as a synthetic intermediate in the pharmaceutical industry for the development of various therapeutic agents. Its unique chemical structure allows for the creation of diverse organic compounds with potential medicinal applications.
Used in Organic Chemistry:
In the field of organic chemistry, (4aS,8aS)-8-(benzoyloxy)-2-methyldecahydroisoquinolinium chloride serves as a valuable compound for further chemical reactions and the synthesis of complex molecules. Its reactivity and structural features make it a useful building block in the design and creation of novel organic compounds.
Used in Antimicrobial Applications:
(4aS,8aS)-8-(benzoyloxy)-2-methyldecahydroisoquinolinium chloride is used as an antimicrobial agent due to its potential to combat various microorganisms. Its effectiveness in inhibiting the growth of bacteria and other pathogens makes it a promising candidate for use in the development of new antimicrobial drugs and treatments.
Used in Antiviral Applications:
(4aS,8aS)-8-(benzoyloxy)-2-methyldecahydroisoquinolinium chloride is also used in antiviral applications, where it has shown potential in inhibiting viral replication and reducing the severity of viral infections. Its antiviral properties are currently being studied for possible inclusion in the development of new antiviral medications.
Check Digit Verification of cas no
The CAS Registry Mumber 63916-73-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,9,1 and 6 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 63916-73:
(7*6)+(6*3)+(5*9)+(4*1)+(3*6)+(2*7)+(1*3)=144
144 % 10 = 4
So 63916-73-4 is a valid CAS Registry Number.
63916-73-4Relevant articles and documents
Synthesis, stereochemistry, and antiarrhythmic activity of some 8 substituted decahydroisoquinolines
Mathison,Morgan
, p. 1136 - 1139 (2007/10/08)
The diastereoisomeric series of 8 substituted 2 methyldecahydroisoquinolines has been synthesized and evaluated as antiarrhythmic agents. Substituted benzoyloxy and benzamido derivatives were found to yield compounds with therapeutic indices considerably higher than that of quinidine. Optimal values were obtained with compounds possessing lipophilic substitutions, most notably the 3,4 dichlorobenzamido grouping. The previous observation of some correlation of trans ring junction stereochemistry with optimal potency was further substantiated by examples in this study. The coumpounds prepared were much less toxic than quinidine. A tetrahydroisoquinoline benzamide derivative was equivalent to quinidine but much less effective as an antiarrhythmic than its decahydro analogs, a finding compatible with earlier studies. Support is provided for the Topliss concept for maximizing activity within a series of compounds where the aromatic moiety is a necessary grouping.
