639468-65-8 Usage
General Description
1-Boc-4-[(4-chlorophenyl)hydroxymethyl]piperidine is a chemical compound with a molecular formula of C16H25ClNO3 and a molecular weight of 309.82 g/mol. It is an organic compound that belongs to the class of piperidines, which are cyclic amines with a six-membered ring. The compound contains a piperidine ring with a hydroxymethyl group and a 4-chlorophenyl substituent. Additionally, it has a tert-butoxycarbonyl (Boc) protective group at the nitrogen atom of the piperidine ring, which serves to protect the amine functionality during synthetic reactions. 1-Boc-4-[(4-chlorophenyl)hydroxyMethyl]piperidine is used in organic synthesis as a building block for the preparation of pharmaceuticals and other bioactive molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 639468-65-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,9,4,6 and 8 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 639468-65:
(8*6)+(7*3)+(6*9)+(5*4)+(4*6)+(3*8)+(2*6)+(1*5)=208
208 % 10 = 8
So 639468-65-8 is a valid CAS Registry Number.
InChI:InChI=1/C17H24ClNO3/c1-17(2,3)22-16(21)19-10-8-13(9-11-19)15(20)12-4-6-14(18)7-5-12/h4-7,13,15,20H,8-11H2,1-3H3
639468-65-8Relevant articles and documents
THERAPEUTIC COMPOUNDS
-
, (2014/01/07)
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof in which m, n, W, X, Y, Z, R, R1, R2, R3 and R4 are as defined in the specification, for use in therapy.
5H-CYCLOPENTA[D]PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS
-
Page/Page column 47, (2009/09/04)
Compounds of Formula I are useful for inhibiting AKT protein kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. Formula (I).
[1H-PYRAZOLO[3, 4-D]PYRIMIDIN-4-YL]-PIPERIDINE OR -PIPERAZINE COMPOUNDS AS SERINE-THEORONINE KINASE MODULATORS (P70S6K, ATK1 AND ATK2) FOR THE TREATMENT OF IMMUNOLOGICAL, INFLAMMATORY AND PROLIFERATIVE DISEASES
-
Page/Page column 92, (2008/06/13)
The invention provides compounds of formula (I) and methods for inhibition of kinases, more specifically p70S6 kinases, and more preferably p70S6, Akt-1 and Akt-2 kinases. The invention provides compounds for modulating protein kinase enzymatic activity f
