64010-12-4

Basic information

• Product Name: 1-BROMO-2-(2-CHLOROETHOXY)BENZENE
• Synonyms: 1-(2-BROMOPHENOXY)-2-CHLOROETHANE;2-(2-CHLOROETHOXY)-BROMOBENZENE;1-BROMO-2-(2-CHLOROETHOXY)BENZENE
• CAS NO: 64010-12-4
• Molecular Formula: C₈H₈BrClO
• Molecular Weight: 235.51
• Mol File: 64010-12-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 273.8 °C at 760 mmHg
• Flash Point: 119.4 °C
• Appearance: /
• Density: 1.495 g/cm³
• Vapor Pressure: 0.00941mmHg at 25°C
• Refractive Index: 1.549
• CAS DataBase Reference: 1-BROMO-2-(2-CHLOROETHOXY)BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-2-(2-CHLOROETHOXY)BENZENE(64010-12-4)
• EPA Substance Registry System: 1-BROMO-2-(2-CHLOROETHOXY)BENZENE(64010-12-4)

Safety Data

• Hazardous Substances Data: 64010-12-4(Hazardous Substances Data)

Usage

General Description

1-Bromo-2-(2-chloroethoxy)benzene is a chemical compound that belongs to the class of organic compounds known as phenol ethers. It is a colorless liquid with a molecular formula of C8H8BrClO, and a molecular weight of 223.51 g/mol. 1-BROMO-2-(2-CHLOROETHOXY)BENZENE is primarily used as an intermediate in the production of pharmaceuticals, dyes, and other organic compounds. It is also used as a solvent in chemical reactions and as a component in the manufacturing of herbicides and insecticides. Due to its potential health hazards and environmental risks, proper handling and disposal procedures are necessary when using this chemical.

InChI:InChI=1/C8H8BrClO/c9-7-3-1-2-4-8(7)11-6-5-10/h1-4H,5-6H2

Upstream product

• 95-56-7 2-hydroxybromobenzene 
• 107-06-2 1,2-dichloro-ethane 

Downstream Products

• 66826-78-6 5-bromo-2,3-dihydrobenzo[b]furan 
• 40492-52-2 2,3-dihydrobenzofuran-5-ol 
• 90843-31-5 1-(2,3-dihydrobenzofuran-5-yl)ethanone 
• 1160918-81-9 4-[(4-methyl-1H-indol-5-yl)amino]-5-[(E)-2-{2-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl}vinyl]nicotinonitrile 
• 1160918-84-2 4-[(4-methyl-1H-indol-5-yl)amino]-5-{(E)-2-[2-(2-pyrrolidin-1-ylethoxy)phenyl]vinyl}nicotinonitrile 
• 1160918-79-5 5-{(E)-2-[2-(2-chloroethoxy)phenyl]vinyl}-4-[(4-methyl-1H-indol-5-yl)amino]nicotinonitrile 
• 64009-34-3 4-(2-Bromo-phenoxy)-2-(2,4-dichloro-phenyl)-butyric acid methyl ester 
• 64009-56-9 2-(2,4-Dichlorphenyl)-4-(2-bromphenoxy)-butanol 
• 64009-20-7 4-(2-Bromo-phenoxy)-2-(2,4-dichloro-phenyl)-butyronitrile 
• 496-16-2 2.3-dihydrobenzofuran 
• 95-56-7 2-hydroxybromobenzene 
• 108-95-2 phenol 

Relevant articles and documents

FUSED PYRIMIDINONE MATRIX METALLOPROTEINASE INHIBITORS

Selective MMP-13 inhibitors are fused pyrimidinones of the formula or a pharmaceutically acceptable salt thereof, wherein: W, together with the carbon atoms to which it is attached, form a 5-membered ring diradical X is O, S, SO, SO2, NR5, or CH 2; B is O or NR5; or A and B are taken together to form--C≡C--; R1, R4, and R 5 are hydrogen, alkyl, alkenyl, alkynyl, (CH2)n aryl, (CH2)n cycloalkyl, C1-C6 alkanoyl, or (CH2)n heteroaryl; R2 and R3 are hydrogen, alkyl, alkenyl, alkynyl CN, NO2, NR 4R5, (CH2)n cycloalkyl, (CH2) n aryl, or (CH2)n heteroaryl; R2 may further be halo; n is an integer of from 0 to 5; and R4 and R5 when taken together with a nitrogen to which they are both attached complete a 3-to 8-membered ring containing carbon atoms and optionally containing O, S, or N, and substituted or unsubstituted; with the proviso that R1 and R3 are not both selected from hydrogen and C1-C6 alkyl.