64019-77-8Relevant articles and documents
Pharmaceutical compounds
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, (2008/06/13)
Pharmaceutical compounds of the formula STR1 in which R1 and R2 are each hydrogen, hydroxyl, halo, C1-4 alkyl, C1-4 alkoxy, acyloxy, --O-glucoside, optionally substituted phenyl or optionally substituted phenyl-C1-4 alkoxy; R3 is tetrazolyl, or and R4 and R5 are each hydrogen, hydroxy, acyloxy, nitro, C1-4 alkyl, C1-4 alkoxy, halo, optionally substituted phenyl, --SO3 H or --NR'R" where R' and R" are each hydrogen or C1-4 alkyl; provided that when R3 is --CR'R".CHR'"CO2 H or tetrazolyl, R1 and R2 are each hydroxyl, halo, C1-4 alkyl, C1-4 alkoxy, acyloxy, --O-glucoside, optionally substituted phenyl or optionally substituted phenyl C1-4 alkoxy; and or a pharmaceutically acceptable salt or ester thereof.
Thiol-reactive Fluorescent probes for Protein Labelling
Corrie, John E. T.
, p. 2975 - 2982 (2007/10/02)
Cyclisation of N-alkylmaleic acids mediated by acetic anhydride in dimethylacetamide in the presence of traces of cobalt naphthenate has been used for efficient assembly of a range of fluorescent maleimide reagents.The fluorescence responses of these reagents to addition of thiol across the maleimide double bond, and to hydrolysis of the meleimide ring, are described.
