640290-92-2

Basic information

• Product Name: 5-(1-{4-[(S)-5-(Acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenyl}-1,2,3,6-tetrahydro-pyridin-4-yl)-isoxazole-3-carboxylic acid ethyl ester
• Synonyms: 5-(1-{4-[(S)-5-(Acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenyl}-1,2,3,6-tetrahydro-pyridin-4-yl)-isoxazole-3-carboxylic acid ethyl ester
• CAS NO: 640290-92-2
• Molecular Weight: 472.473
• Mol File: 640290-92-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(1-{4-[(S)-5-(Acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenyl}-1,2,3,6-tetrahydro-pyridin-4-yl)-isoxazole-3-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(1-{4-[(S)-5-(Acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenyl}-1,2,3,6-tetrahydro-pyridin-4-yl)-isoxazole-3-carboxylic acid ethyl ester(640290-92-2)
• EPA Substance Registry System: 5-(1-{4-[(S)-5-(Acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenyl}-1,2,3,6-tetrahydro-pyridin-4-yl)-isoxazole-3-carboxylic acid ethyl ester(640290-92-2)

Safety Data

• Hazardous Substances Data: 640290-92-2(Hazardous Substances Data)

Upstream product

• 172966-53-9 (S)-N-{3-[3-fluoro-4-(4-oxo-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide 
• 126085-91-4 5-tributylstannanyl-isoxazole-3-carboxylic acid ethyl ester 
• 640290-76-2 Trifluoro-methanesulfonic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenyl}-1,2,3,6-tetrahydro-pyridin-4-yl ester 

Relevant articles and documents

Synthesis and in vitro activity of novel isoxazolyl tetrahydropyridinyl oxazolidinone antibacterial agents

A series of isoxazolyl tetrahydropyridinyl oxazolidinones with various substituents at the 3-position of the isoxazole ring have been synthesized and their in vitro antibacterial activities (MIC) were evaluated against several Gram-positive strains including the resistant strains of Staphyloccus and Enterococcus, such as MRSA and VRE. One of the most potent compounds synthesized, 4f, showed comparable or better activity against selected bacterial strains than those of linezolid and vancomycin.