64063-37-2Relevant articles and documents
Preparation of 5-acylamino-1,2,4-triazole-3-sulfonamides
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, (2008/06/13)
5-Acylamino-1,2,4-triazole-3-sulfonamides, which are useful intermediates for the preparation of 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamide herbicides are prepared from 5-amino-3-mercapto-1,2,4-triazole by sequential acylation to 5-acylamino-3-mercapto-1,2,4-triazoles, chlorination to 5-acylamino-3-chlorosulfonyl-1,2,4-triazoles, and condensation with substituted anilines to 5-acylamino-1,2,4-triazole-3-sulfonamides. 5-Acylamino-3-chlorosulfonyl-1,2,4-triazole compounds are key intermediates in the process.
Synthesis of 2,6-disubstituted and 2,3,6-trisubstituted anilines
Pews,Hunter,Wehrmeyer
, p. 4809 - 4820 (2007/10/02)
A number of 2,6-disubstituted and 2,3,6-trisubstituted anilines have been prepared via the selective para dehalogenation of the corresponding anilines. Modification of the substituents on the amino nitrogen demonstrates that the selectivity is derived from steric rather than electronic effects. The effects of the choice of formate hydrogen donor, Pd catalyst, solvent, and temperature upon the efficiency and selectivity of the dehalogenation are discussed.
A novel synthesis of 2,6-disubstituted and 2,3,6-trisubstituted anilines
Pews,Hunter,Wehmeyer
, p. 7191 - 7194 (2007/10/02)
2,6-Disubstituted and 2,3,6-trisubstituted anilines have been synthesized by a four-step approachy involving the selective reduction of a para halogen of the diacetanilide derivatives utilizing a palladium-on-carbon catalyst and formic acid salts as the in situ hydrogen donor.
