64088-81-9Relevant articles and documents
An expedient large-scale preparation of a dibenz[b,e]oxepinone derivative
Lee, Thomas B.K.,Tebben, Andrew J.,Weiberth, Franz J.,Wong, George S.K.
, p. 747 - 751 (2007/10/03)
A convenient, large-scale synthesis of a dibenz[b,e]oxepinone derivative is described. The dibenz[-b,e]oxepinone ring system is constructed using an iron chloride catalyzed intramolecular Friedel-Crafts cyclization of an appropriate phenoxymethylbenzoic acid chloride in toluene, reagents and conditions that are economically and environmentally compatible with large- scale preparation.
Method of treating dermal inflammations
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, (2008/06/13)
A method of treating dermal inflammation by topically administering to a patient an effective amount of a 6,11-dihydrodibenz[b,e]oxepinalkanoic acid, physiologically tolerable salt thereof, derivative thereof, or diacid precursor thereof is described.