64158-25-4

Basic information

• Product Name: 1,2-Ethanediol, 1,2-bis(2-methylphenyl)-
• CAS NO: 64158-25-4
• Molecular Formula: C16H18O2
• Molecular Weight: 242.318
• Mol File: 64158-25-4.mol
• Article Data: 33

Chemical Properties

• CAS DataBase Reference: 1,2-Ethanediol, 1,2-bis(2-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Ethanediol, 1,2-bis(2-methylphenyl)-(64158-25-4)
• EPA Substance Registry System: 1,2-Ethanediol, 1,2-bis(2-methylphenyl)-(64158-25-4)

Safety Data

• Hazardous Substances Data: 64158-25-4(Hazardous Substances Data)

Upstream product

• 529-20-4 2-methylphenyl aldehyde 
• 52340-78-0 (R,R)-hydroxybenzoin 
• 74-88-4 methyl iodide 
• 89-95-2 2-methyl-benzyl alcohol 
• 36888-18-3 (E)-2,2'-dimethylstilbene 
• 4389-39-3 2-hydroxy-1,2-bis(2-methylphenyl)ethanone 
• 64-17-5 ethanol 
• 7732-18-5 water 
• 127-08-2 potassium acetate 
• 141-78-6 ethyl acetate 
• 51608-60-7 N-(benzylidene)-p-methylbenzenesulfonamide 
• 108-24-7 acetic anhydride 
• 932-31-0 ortho-tolylmagnesium bromide 
• 131543-46-9 Glyoxal 

Downstream Products

• 916525-60-5 1,2-bis(2-methylphenyl)-2-[(7,8,8-trimethyloctahydro-4,7-methanobenzo[b]furan-2-yl)oxy]ethanol 
• 4389-39-3 2-hydroxy-1,2-bis(2-methylphenyl)ethanone 
• 916525-65-0 [1,2-bis(2-methylphenyl)-2-(2-methylpropoxy)ethoxy]-7,8,8-trimethyloctahydro-4,7-methanobenzo[b]furan 
• 916525-77-4 oxophenylacetic acid (1R,2S)-1,2-bis(2-methylphenyl)-2-(2-methylpropoxy)ethyl ester 
• 916525-82-1 hydroxy(phenyl)acetic acid (1R,2S)-1,2-bis(2-methylphenyl)-2-(2-methylpropoxy)ethyl ester 
• 916525-72-9 (1R,2S)-1,2-bis(2-methylphenyl)-2-(2-methylpropoxy)ethanol 
• 118-90-1 ortho-methylbenzoic acid 
• 529-20-4 2-methylphenyl aldehyde 
• 2048-07-9 1,2-bis(2-methylphenyl)-1,2-ethanedione 
• 34712-68-0 meso-2,2'-Dimethylhydrobenzoin-sulfit 

Relevant articles and documents

Oxidative carbon-carbon bond cleavage of 1,2-diols to carboxylic acids/ketones by an inorganic-ligand supported iron catalyst

The carbon-carbon bond cleavage of 1,2-diols is an important chemical transformation. Although traditional stoichiometric and catalytic oxidation methods have been widely used for this transformation, an efficient and valuable method should be further explored from the views of reusable catalysts, less waste, and convenient procedures. Herein an inorganic-ligand supported iron catalyst (NH4)3[FeMo6O18(OH)6]·7H2O was described as a heterogeneous molecular catalyst in acetic acid for this transformation in which hydrogen peroxide was used as the terminal oxidant. Under the optimized reaction conditions, carbon-carbon bond cleavage of 1,2-diols could be achieved in almost all cases and carboxylic acids or ketones could be afforded with a high conversion rate and high selectivity. Furthermore, the catalytic system was used efficiently to degrade renewable biomass oleic acid. Mechanistic insights based on the observation of the possible intermediates and control experiments are presented.

Metal-free thermal organocatalytic pinacol coupling of arylaldehydes using an isonicotinate catalyst with bis(pinacolato)diboron

The metal-free thermal organocatalytic pinacol coupling of arylaldehydes has been developed. The intermolecular coupling of arylaldehydes catalyzed byt-butyl isonicotinate with bis(pinacolato)diboron as the co-reducing agent afforded 1,2-diphenylethane-1,2-diols. This reaction was also applicable to the intramolecular coupling of 1,1′-biphenyl-2,2′-dicarbaldehydes to afford 9,10-dihydrophenanthrene-9,10-diols. Various functional groups were tolerated under this coupling condition.

Diborative Reduction of Alkynes to 1,2-Diboryl-1,2-Dimetalloalkanes: Its Application for the Synthesis of Diverse 1,2-Bis(boronate)s

Reduction of alkynes with alkali metals in the presence of B2pin2 results in diboration of alkynes. Distinct from conventional dissolving metal hydrogenations, two carbon-boron bonds and also two carbon-alkali metal bonds can be constructed in one operation to form 1,2-diboryl-1,2-dimetalloalkanes. The 1,2-diboryl-1,2-dimetalloalkanes generated are readily convertible to a wide range of vicinal bis(boronate)s. In particular, oxidation of the 1,2-dianionic species provides (E)-1,2-diborylalkenes, unique anti-selective diboration of alkynes being thus executed.