64162-07-8

Basic information

• Product Name: ethyl 2-aminocyclohexanecarboxylate
• Synonyms: ethyl 2-aminocyclohexanecarboxylate;ethyl 2-aminocyclohexane-1-carboxylate
• CAS NO: 64162-07-8
• Molecular Formula: C₉H₁₇NO₂
• Molecular Weight: 171.23678
• Mol File: 64162-07-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 235.3°C at 760 mmHg
• Flash Point: 101.5°C
• Appearance: /
• Density: 1.018g/cm³
• Vapor Pressure: 0.0505mmHg at 25°C
• Refractive Index: 1.468
• Storage Temp.: Refrigerator, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: ethyl 2-aminocyclohexanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-aminocyclohexanecarboxylate(64162-07-8)
• EPA Substance Registry System: ethyl 2-aminocyclohexanecarboxylate(64162-07-8)

Safety Data

• Hazardous Substances Data: 64162-07-8(Hazardous Substances Data)

Usage

Uses

Ethyl 2-Aminocyclohexane-1-carboxylate can be used as anti-arrythmic agents.

InChI:InChI=1/C9H17NO2/c1-2-12-9(11)7-5-3-4-6-8(7)10/h7-8H,2-6,10H2,1H3

Upstream product

• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 1128-00-3 ethyl 2-aminocyclohex-1-ene-1-carboxylate 
• 1469-49-4 6-carbamoylcyclohex-3-enecarboxylic acid 
• 64-17-5 ethanol 
• 6294-84-4 cis-1-carboxy-2-(aminocarboxyl)-2-cyclohexane 
• 118-92-3 anthranilic acid 

Downstream Products

• 24716-89-0 cis-2-amino-1-aminomethylcyclohexane 
• 24716-87-8 cis-decahydroquinazoline 
• 114798-82-2 methyl 2-n-butyl-4-chloro-1-<<4-<2-(trifluoromethanesulfonamido)cyclohexanecarboxamido>phenyl>methyl>imidazole-5-acetate 
• 114772-22-4 trans-2-(trifluoromethanesulfonamido)cyclohexanecarboxylic acid 
• 114772-24-6 (1R,2R)-2-Trifluoromethanesulfonylamino-cyclohexanecarbonyl chloride 
• 114745-56-1 {2-[((1S,2S)-2-Heptanoylamino-cyclohexanecarbonyl)-amino]-acetylamino}-acetic acid ethyl ester 
• 114950-65-1 (r-4a,t-2,c-8a)-3-methyl-2-p-nitrobenzylideneperhydroquinazoline-4-one 
• 114950-65-1 (r-4a,c-2,c-8a)-3-methyl-2-p-nitrobenzylideneperhydroquinazoline-4-one 
• 114950-65-1 (r-4a,t-2,t-8a)-3-methyl-2-p-nitrophenylperhydroquinazolin-4-one 
• 114950-66-2 (1R,2S)-2-{[1-(4-Nitro-phenyl)-meth-(E)-ylidene]-amino}-cyclohexanecarboxylic acid amide 
• 114950-66-2 (1S,2S)-2-{[1-(4-Nitro-phenyl)-meth-(E)-ylidene]-amino}-cyclohexanecarboxylic acid amide 
• 114950-64-0 (r-4a,c-2,c-8a)-2-p-nitrophenylperhydroquinazolin-4-one 
• 114950-64-0 (r-4a,t-2,c-8a)-2-p-nitrophenylperhydroquinazolin-4-one 
• 114950-64-0 (r-4a,t-2,t-8a)-2-p-nitrophenylperhydroquinazolin-4-one 

Relevant articles and documents

Synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols or 3-amino alcohols using iodobenzene dichloride and sodium azide

A general and efficient method for the synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols and 3-amino alcohols has been developed using the same reagent combination of iodobenzene dichloride (PhICl2) and sodium azide (NaN3).

EXPERIMENTAL STUDIES OF THE ANOMERIC EFFECT. PART 2 RING INVERSION AND NITROGEN INVERSION EQUILIBRIA IN CIS-DECAHYDROQUINAZOLINES

The positions of conformational equilibria due to the double ring inversion in cis-decahydroquinazoline (7-->//07-->8 1.08 kcal mol-1; -ΔG09-->10 1.10 kcal mol-1) for the conformation which would allow the lone pairs on N(1) and N(3) to lie on the hindered 'inside' face of the molecules.However, the values of 3J(CHNH) coupling constants for both cis-decahydro-3-methylquinazoline (10) and cis (4aH, 8aH) cis (2H, 8aH)-decahydro-2,3-dimethylquinazoline (14) show that the N-inversion equilibrium at N(1) prefers the conformation in which N(1)-H is 'inside' (axial), and N(1)-lone pair equatorial, thus demonstrating the ability of the anomeric effect to outweigh steric repulsions.