64179-17-5

Basic information

• Product Name: 2-IODOMETHYL-1,4-DIOXANE
• Synonyms: 2-IODOMETHYL-1,4-DIOXANE
• CAS NO: 64179-17-5
• Molecular Formula: C₅H₉IO₂
• Molecular Weight: 228.03
• Mol File: 64179-17-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 48℃
• Boiling Point: 240℃
• Flash Point: 99℃
• Appearance: /
• Density: 1.775
• Vapor Pressure: 0.0595mmHg at 25°C
• Refractive Index: 1.5242
• CAS DataBase Reference: 2-IODOMETHYL-1,4-DIOXANE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-IODOMETHYL-1,4-DIOXANE(64179-17-5)
• EPA Substance Registry System: 2-IODOMETHYL-1,4-DIOXANE(64179-17-5)

Safety Data

• Hazardous Substances Data: 64179-17-5(Hazardous Substances Data)

Usage

General Description

2-Iodomethyl-1,4-Dioxane is a chemical compound with the molecular formula C5H9IO2. It is an iodinated derivative of 1,4-dioxane, which is a heterocyclic organic compound. 2-Iodomethyl-1,4-Dioxane is commonly used as a reagent in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. It is also used as an intermediate in the manufacturing of other chemicals and as a solvent in certain industrial processes. However, it is important to handle this compound with caution, as it is classified as an irritant and may be harmful if ingested, inhaled, or in contact with the skin. Additionally, it may have environmental and health hazards if not handled and disposed of properly.

InChI:InChI=1/C5H9IO2/c6-3-5-4-7-1-2-8-5/h5H,1-4H2

Upstream product

• 74-88-4 methyl iodide 
• 111-45-5 ethylene glycol monoallyl ether 

Downstream Products

• 329217-45-0 1-phenylmethyl-4(dioxan-2-ylmethyl)piperazine 
• 68391-40-2 acetoxymethyl-[1,4]dioxane 
• 1112169-37-5 rac-6-(2-((1,4-dioxan-2-yl)methyl)-2H-tetrazol-5-yl)-N-(4-fluoro-3-methoxybenzyl)-2-methyl-pyrimidine-4-carboxamide 
• 1112169-35-3 rac-6-(2-((1,4-dioxan-2-yl)methyl)-2H-tetrazol-5-yl)-N-(3-methoxybenzyl)-2-methyl-pyrimidine-4-carboxamide 
• 329217-47-2 2-piperazinylmethyl-1,4-dioxane 

Relevant articles and documents

6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS

The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.

Benzimidazole compound

An object of the present invention is to provide a novel chemical compound useful as a therapeutic or prophylactic agent for acid-related diseases, having an excellent inhibitory effect against gastric acid secretion, an excellent effect of maintaining the inhibitory effect against gastric acid secretion, thereby maintaining intragastric pH high for a long time, and having more safety and appropriate physicochemical stability. Provided is a compound represented by where R1 and R3 may be the same or different and each represent a hydrogen atom or a C1-C6 alkyl group; R2 represents (5,5-dimethyl-1,3-dioxan-2-yl)methoxy group, 5,7-dioxaspiro[2.5]oct-6-ylmethoxy group, 1,5,9-trioxaspiro[5.5]undec-3-ylmethoxy group, or (2,2-dimethyl-1,3-dioxan-5-yl)methoxy group; R4, R5, R6 and R7 represent a hydrogen atom, halogen atom, C1-C6 alkyl group, C1-C6 haloalkyl group, C1-C6 alkoxy group or C1-C6 haloalkoxy group; and W1 represents a single bond, methylene or ethylene group, a salt thereof or a solvate of these.

PHOSPHORYLATED DERIVATIVES OF p-DIOXANE-2-METHANOL

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