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64190-49-4

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64190-49-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 64190-49-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,1,9 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 64190-49:
(7*6)+(6*4)+(5*1)+(4*9)+(3*0)+(2*4)+(1*9)=124
124 % 10 = 4
So 64190-49-4 is a valid CAS Registry Number.

64190-49-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-4-(Benzyloxy)-3-methylbutanoic acid

1.2 Other means of identification

Product number -
Other names (3S)-4-benzyloxy-3-methylbutyric acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:64190-49-4 SDS

64190-49-4Relevant articles and documents

Chemical synthesis enables biochemical and antibacterial evaluation of streptolydigin antibiotics

Pronin, Sergey V.,Martinez, Anthony,Kuznedelov, Konstantin,Severinov, Konstantin,Shuman, Howard A.,Kozmin, Sergey A.

, p. 12172 - 12184 (2011/10/04)

Inhibition of bacterial transcription represents an effective and clinically validated anti-infective chemotherapeutic strategy. We describe the evolution of our approach to the streptolydigin class of antibiotics that target bacterial RNA polymerases (RN

SN2 ring opening of β-lactones: An alternative to catalytic asymmetric conjugate additions

Nelson, Scott G.,Wan, Zhonghui,Stan, Magdalena A.

, p. 4680 - 4683 (2007/10/03)

Merging catalytic asymmetric acyl halide-aldehyde cyclocondensation (AAC) reactions with ensuing Grignard-mediated ring opening of the derived enantiomerically enriched β-lactones is presented as a generally useful asymmetric synthesis of β-disubstituted

Synthesis of Optically Active Bifunctional Isoprenoid Building Blocks by Rhodium(I)-Catalyzed Asymmetric Allylamine to Enamine Isomerization

Schmid, Rudolf,Hansen, Hans-Juergen

, p. 1258 - 1275 (2007/10/02)

The application of the known asymmetric allylamine to enamine isomerization methodology to bifunctional C5-isoprenoid allylic amines of types IId and IIe (Scheme 1) is described.It is shown that a number of such substrates can be isomerized with enantioselectivities of >90percent ee using cationic RhI complexes containing (6,6'-dimethylbiphenyl-2,2'-diyl)bis(diphenylphosphine) (BIPHEMP; 9) as asymmetry-inducing ligand (Scheme 2, Tables 1 and 2).Synthetically most useful is the isomerization of the benzyloxy derivative 10a into the (E)-enamine 11a.This isomerization proceeds with very high enantioselectivity (98-99percent ee) and affords, after enamine hydrolysis, the optically active 4-(benzyloxy)-3-methylbutanals ((R)- or (S)-12) in chemical yields of ca. 90percent.In conjunction, a short synthetic route to the starting material 10a has been developed which has a Pd-catalyzed amination of isoprene epoxide (30) as the key step.Thus, convenient and practical access to the optically active aldehydes (R)- and (S)-12 is now at hand.These aldehydes are useful optically active bifunctional building blocks for isoprenoid homologation.

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