6421-88-1 Usage
Description
2-(4-aminophenoxy)ethanol, also known as 4-(2-hydroxyethoxy)aniline, is an organic compound with the chemical formula C8H11NO2. It is a colorless to pale yellow liquid that is used in the manufacturing of various products, including dyes, pharmaceuticals, and surfactants. 2-(4-aminophenoxy)ethanol is also utilized as an intermediate in the production of other chemicals and is known for its ability to form stable complexes with metal ions. 2-(4-aminophenoxy)ethanol is considered to be a relatively low toxicity compound and is generally regarded as safe for use in approved applications.
Uses
Used in Dye Industry:
2-(4-aminophenoxy)ethanol is used as a chemical intermediate for the synthesis of various dyes, providing a wide range of colors and properties for different applications.
Used in Pharmaceutical Industry:
2-(4-aminophenoxy)ethanol is used as a building block in the development of pharmaceutical compounds, contributing to the creation of new drugs with potential therapeutic benefits.
Used in Surfactant Industry:
2-(4-aminophenoxy)ethanol is used as a component in the formulation of surfactants, enhancing their performance in various cleaning and industrial processes.
Used in Chemical Intermediates:
2-(4-aminophenoxy)ethanol is used as an intermediate in the production of other chemicals, enabling the synthesis of a variety of compounds for different industries.
Used in Metal Ion Complexation:
2-(4-aminophenoxy)ethanol is used for its ability to form stable complexes with metal ions, which can be useful in various applications such as catalysis, environmental remediation, and analytical chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 6421-88-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,4,2 and 1 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6421-88:
(6*6)+(5*4)+(4*2)+(3*1)+(2*8)+(1*8)=91
91 % 10 = 1
So 6421-88-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NO2/c9-7-1-3-8(4-2-7)11-6-5-10/h1-4,10H,5-6,9H2
6421-88-1Relevant articles and documents
COMPOUNDS TARGETING RNA-BINDING PROTEINS OR RNA-MODIFYING PROTEINS
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, (2021/09/11)
The invention relates to a compound represented by Formula (I): or a pharmaceutically acceptable salt thereof, compositions comprising the same and methods of preparing and using the same. The variables are described herein.
INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS AND USE OF SAME IN MEDICINE
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Paragraph 0254-0255; 0257, (2020/11/30)
The present invention relates to a compound represented by formula I, a pharmaceutical composition containing the compound of formula I, a method for inhibiting indoleamine 2,3-dioxygenase, and its use in medicine.
Design, synthesis, and biological evaluation of some novel 4-aminoquinazolines as Pan-PI3K inhibitors
Ding, Huai-Wei,Wang, Shu,Qin, Xiao-Chun,Wang, Jian,Song, Hong-Rui,Zhao, Qing-Chun,Song, Shao-Jiang
, p. 2729 - 2740 (2019/05/17)
A series of 4-aminoquinazolines derivatives containing hydrophilic group were designed and identified as potent Pan-PI3K inhibitors in this study. The results of antiproliferative assays in vitro showed that this series of compounds had strong inhibition of tumor growth, especially compound 7b for MCF-7 cells but weak inhibition to normal cells. PI3K kinase assay showed that 7b had high activity for three PI3K isoforms with the IC50 values of picomole. The western blot assay indicated that 7b could decrease the phospho-Akt (S473) in a dose-dependent manner. Further experiments showed that 7b could induce apoptosis in MCF-7 cells. Four key hydrogen bonding interactions were found in the docking of 7b with PI3K kinase. All these results suggested that 7b is a potent PI3K inhibitor and could be considered as a potential candidate for the development of anticancer agents.
