6425-26-9Relevant articles and documents
A simple and regioselective α-bromination of alkyl aromatic compounds by two-phase electrolysis
Raju,Kulangiappar,Anbu Kulandainathan,Muthukumaran
, p. 7047 - 7050 (2005)
Electrochemical bromination of toluene and substituted toluenes by two-phase electrolysis yields the corresponding α-brominated products. The reaction has been carried out in a single compartment cell with platinum electrodes at 0°C in chloroform using an aqueous sodium bromide solution (60%) containing a catalytic amount of HBr. Two-phase electrolysis results in high yields (60-95%) of monobromo compounds with very high regioselectivity (>95%).
Easy access for the synthesis of 2-aryl 2,3-dihydroquinazolin-4(1H)-ones using gem-dibromomethylarenes as synthetic aldehyde equivalent
Narasimhamurthy, Kereyagalahally H.,Chandrappa, Siddappa,Sharath Kumar, Kothanahally S.,Harsha, Kachigere B.,Ananda, Hanumappa,Rangappa, Kanchugarakoppal S.
, p. 34479 - 34486 (2014/10/16)
One step synthesis of 2,3-dihydroquinazolin-4(1H)-ones from gem-dibromomethylarenes using 2-aminobenzamide is described. Gem-dibromomethylarenes are used as aldehyde equivalent for the efficient synthesis of 2,3-dihydroquinazolin-4(1H)-ones, this synthesis takes shorter reaction time with quick isolation and excellent product yield. This journal is the Partner Organisations 2014.
