64274-28-8Relevant articles and documents
Bianco et al.
, p. 847,848,850 (1977)
THE QUANTITATIVE ISOLATION AND ANTIMICROBIAL ACTIVITY OF THE AGLYCONE OF AUCUBIN
Davini, Enrico,Iavarone, Carlo,Trogolo, Corrado,Aureli, Paolo,Pasolini, Beatrice
, p. 2420 - 2422 (1986)
Despite the reported instability of iridoid aglycones, a new procedure was developed for the quantitative extraction of aucubigenin from an enzymatic hydrolysate of aucubin.The aglycone was obtained in crystalline form and was for the first time spectroscopically characterized (1H and 13C NMR spectra).Its antimicrobial activity against yeasts, bacteria and moulds was also accurately tested.Key Word Index - Aucubin; aucubigenin; iridoid aglycones; aglycone extraction; 1H and 13C NMR; antimicrobial activity.
Determination of antibacterial activity of aucubigenin and aucubin
Li, Yang,Chen, Lei,Han, Guijun,Zhou, Junhui,Zhao, Ye
, p. 559 - 561 (2014)
Because of the previously conflicted reports, the aucubigenin and aucubin have been reinvestigated for their antibacterial activities by a sensitive standardized micro-well dilution with automated spectrophotometric method, compared with paper disc diffusion method. The micro-well dilution assay was more accurate than paper disc diffusion method. The results showed that aucubin exhibited no antibacterial activity, while aucubigenin showed remarkable antibacterial activity against all of the tested bacteria. Aucubigenin was particularly more effective against Staphylococcus aureus with MIC value of 0.0313 mg/mL and MBC value of 0.0625 mg/mL, respectively.
Studies on iridoid-related compounds. IV. Antitumor activity of iridoid aglycones
Isiguro,Yamaki,Takagi,Ikeda,Kawakami,Ito,Nose
, p. 2375 - 2379 (2007/10/02)
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