643087-83-6

Basic information

• Product Name: Carbamic acid, [1-(4-aminophenyl)-3-pyrrolidinyl]methyl-, 1,1-dimethylethyl ester
• CAS NO: 643087-83-6
• Molecular Formula: C16H25N3O2
• Molecular Weight: 291.393
• Mol File: 643087-83-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [1-(4-aminophenyl)-3-pyrrolidinyl]methyl-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [1-(4-aminophenyl)-3-pyrrolidinyl]methyl-, 1,1-dimethylethyl ester(643087-83-6)
• EPA Substance Registry System: Carbamic acid, [1-(4-aminophenyl)-3-pyrrolidinyl]methyl-, 1,1-dimethylethyl ester(643087-83-6)

Safety Data

• Hazardous Substances Data: 643087-83-6(Hazardous Substances Data)

Upstream product

• 350-46-9 4-Fluoronitrobenzene 
• 169750-01-0 3-<(t-butyloxycarbonyl)methylamino>-pyrrolidine 
• 863401-75-6 methyl-[1-(4-nitro-phenyl)-pyrrolidin-3-yl]-carbamic acid tert-butyl ester 

Downstream Products

• 863401-89-2 biphenyl-4-carboxylic acid [4-(3-methylamino-pyrrolidin-1-yl)-phenyl]-amide 
• 863401-88-1 (1-{4-[(biphenyl-4-carbonyl)-amino]-phenyl}-pyrrolidin-3-yl)-methyl-carbamic acid tert-butyl ester 

Relevant articles and documents

1-(4-Amino-phenyl)-pyrrolidin-3-yl-amine and 6-(3-amino-pyrrolidin-1-yl)- pyridin-3-yl-amine derivatives as melanin-concentrating hormone receptor-1 antagonists

Derivatives of 1-(4-amino-phenyl)-pyrrolidin-3-yl-amine and 6-(3-amino-pyrrolidin-1-yl)-pyridin-3-yl-amine were identified as potent and functionally active MCH-R1 antagonists. One compound with Ki = 2.3 nM demonstrated good oral bioavailabilit