64334-95-8

Basic information

• Product Name: 4(1H)-Quinolinone, 2-methyl-7-nitro-
• Synonyms: 2-methyl-7-nitro-4-quinolone
• CAS NO: 64334-95-8
• Molecular Formula: C10H8N2O3
• Molecular Weight: 204.18200
• Mol File: 64334-95-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4(1H)-Quinolinone, 2-methyl-7-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Quinolinone, 2-methyl-7-nitro-(64334-95-8)
• EPA Substance Registry System: 4(1H)-Quinolinone, 2-methyl-7-nitro-(64334-95-8)

Safety Data

• Hazardous Substances Data: 64334-95-8(Hazardous Substances Data)

Upstream product

• 195433-10-4 2,2-dimethyl-5-[1-(3-nitroanilino)ethylidene]-1,3-dioxane-4,6-dione 

Downstream Products

• 1390617-52-3 C₁₉H₁₉N₃O₂ 
• 1390617-51-2 C₂₄H₂₁N₃O₂ 

Relevant articles and documents

Synthesis and pharmacological evaluation of new cysLT1 receptor antagonists

This paper describes the synthesis and pharmacological evaluation of three series of compounds 4a-b, 13a-k and 19, structurally related to the known potent cysLT1 receptor antagonists RG-12553, IC1-204219 and ONO-1078, respectively. The common structural feature of these new series is the presence of a 4-quinolone nucleus acting as a template for substitution of the aromatic nucleus present in the prototype antagonists. We describe the evolution of these series leading to antagonists with potency at nanomolar concentrations in vitro.