64354-50-3 Usage
Description
5-METHYL-2-PHENYL-3-FUROIC ACID is a chemical compound with the molecular formula C12H10O3. It is a furoic acid derivative, consisting of a furan ring with a carboxylic acid group and a phenyl group. This white to off-white crystalline powder is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its various biological activities, including potential antitumor and antibacterial properties. It is typically handled and stored in a controlled laboratory environment.
Uses
Used in Pharmaceutical Industry:
5-METHYL-2-PHENYL-3-FUROIC ACID is used as an intermediate in the synthesis of pharmaceuticals for its potential antitumor properties. It contributes to the development of drugs that target various types of cancer, offering a promising avenue for cancer treatment.
Used in Agrochemical Industry:
In the agrochemical sector, 5-METHYL-2-PHENYL-3-FUROIC ACID is utilized as a precursor in the production of agrochemicals, specifically for its potential antibacterial properties. This application aids in the development of products that can protect crops from bacterial infections, thereby enhancing agricultural productivity.
Used in Research and Development:
5-METHYL-2-PHENYL-3-FUROIC ACID is also used as a research compound for studying its biological activities and potential applications in medicine and agriculture. This involves exploring its interactions with biological systems and evaluating its efficacy and safety in various settings.
Check Digit Verification of cas no
The CAS Registry Mumber 64354-50-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,3,5 and 4 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 64354-50:
(7*6)+(6*4)+(5*3)+(4*5)+(3*4)+(2*5)+(1*0)=123
123 % 10 = 3
So 64354-50-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H10O3/c1-8-7-10(12(13)14)11(15-8)9-5-3-2-4-6-9/h2-7H,1H3,(H,13,14)
64354-50-3Relevant articles and documents
Synthesis, insecticidal activities, and SAR studies of novel piperazine-containing heterocyclic mono-/di-/tri-amide derivatives
Li, Huan,Liu, Hang,Zhang, Yan,Yang, Na,Xiong, Lixia,Li, Zhengming,Wang, Baolei
supporting information, p. 2893 - 2898 (2021/05/19)
Diamide compounds such as chlorantraniliprole, a famous anthranilic diamide insecticide targeting the insect ryanodine receptor (RyR), have received continuous attention in pesticide research during the past 15 years owing to their excellent insecticidal potentials. With the aim of discovering new heterocyclic pesticides used for crop protection, based on the structural information of compound M from the reported pharmacophore-based virtual screening for RyR insecticides and diamide compound, a series of new heterocyclic mono-, di-, and tri-amide derivatives containing piperazine moiety have been synthesized in this paper. The new compounds were identified and confirmed by melting point, 1H NMR, 13C NMR and HRMS. Compound M was firstly validated for insecticidal activities, and the new synthesized compounds were all made comprehensive insecticidal evaluations against diamondback moth and oriental armyworm. The bioassay results showed that some of the compounds exhibit favorable insecticidal potentials, particularly some novel piperazine-containing heterocyclic mono-/di-/tri-amide derivatives such as 8g, 14a, 15a, 15g, 15i, 15j, 15k, 15l, and 15m could be used as new insecticidal leading structures for further study (e.g., towards diamondback moth, 15i-15m LC50: 0.0022?0.0081 mg/L). The structure-activity relationships of the compounds discussed in detail provide useful guidance for further design and development of new insecticides.