64360-47-0

Basic information

• Product Name: METHYL 2-(4-HYDROXY-3-METHYLPHENYL)ACETATE
• Synonyms: METHYL 2-(4-HYDROXY-3-METHYLPHENYL)ACETATE;(4-Hydroxy-3-methyl-phenyl)-acetic acid methyl ester
• CAS NO: 64360-47-0
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.2
• Product Categories: Aromatic Phenylacetic Acids and Derivatives;Aromatics;Intermediates
• Mol File: 64360-47-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 285.9 °C at 760 mmHg
• Flash Point: 119.9 °C
• Appearance: /
• Density: 1.148 g/cm³
• Vapor Pressure: 0.00158mmHg at 25°C
• Refractive Index: 1.535
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 10.12±0.18(Predicted)
• CAS DataBase Reference: METHYL 2-(4-HYDROXY-3-METHYLPHENYL)ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-(4-HYDROXY-3-METHYLPHENYL)ACETATE(64360-47-0)
• EPA Substance Registry System: METHYL 2-(4-HYDROXY-3-METHYLPHENYL)ACETATE(64360-47-0)

Safety Data

• Hazardous Substances Data: 64360-47-0(Hazardous Substances Data)

Usage

Description

METHYL 2-(4-HYDROXY-3-METHYLPHENYL)ACETATE, also known as (4-Hydroxy-3-methylphenyl)acetic Acid Methyl Ester, is an ester derivative of a disubstituted phenylacetic acid. It is a chemical compound with a molecular structure that features a methyl ester group attached to a phenyl ring with hydroxy and methyl substituents. METHYL 2-(4-HYDROXY-3-METHYLPHENYL)ACETATE is known for its potential applications in the pharmaceutical and chemical industries due to its unique properties and reactivity.

Uses

Used in Pharmaceutical Industry:
METHYL 2-(4-HYDROXY-3-METHYLPHENYL)ACETATE is used as an intermediate compound for the synthesis of anti-inflammatory agents. Its chemical structure allows it to be a key component in the development of drugs that target inflammation and related conditions. The presence of the hydroxy and methyl groups on the phenyl ring provides opportunities for further chemical modifications and the creation of more potent and selective anti-inflammatory drugs.
Used in Chemical Industry:
METHYL 2-(4-HYDROXY-3-METHYLPHENYL)ACETATE is also used as a building block for the preparation of other biologically active compounds. Its versatile structure makes it a valuable starting material for the synthesis of various organic compounds with potential applications in the fields of medicine, agriculture, and materials science. The ester functionality can be further modified or used as a protecting group during the synthesis of more complex molecules.

InChI:InChI=1/C10H12O3/c1-7-5-8(3-4-9(7)11)6-10(12)13-2/h3-5,11H,6H2,1-2H3

Upstream product

• 75391-57-0 2-(4-methoxy-3-methylphenyl)acetonitrile 
• 578-58-5 2-methylmethoxybenzene 
• 67-56-1 methanol 
• 60736-71-2 3-methyl-4-methoxybenzyl chloride 
• 143-33-9 sodium cyanide 

Downstream Products

• 1573056-54-8 4-{4-[(4-chloro-3-trifluoromethylphenylcarbamoyl)methyl]-2-methylphenoxy}-pyridine-2-carboxyl acid methylamide 
• 29121-56-0 (4-hydroxy-3-methylphenyl)acetic acid 
• 1573056-52-6 N-(4-chloro-3-trifluoromethylphenyl)-2-(4-hydroxy-3-methylphenyl)acetamide 
• 1259022-96-2 methyl 2-(3-methyl-4-(trifluoromethylsulfonyloxy)phenyl)acetate 
• 64360-42-5 (4-benzyloxy-3-methyl-phenyl)-acetic acid 
• 64360-43-6 [4-(4-Ethyl-benzyloxy)-3-methyl-phenyl]-acetic acid 
• 64360-45-8 [4-(4-Allyloxy-3-chloro-benzyloxy)-3-methyl-phenyl]-acetic acid 
• 64360-46-9 [4-(3-Chloro-4-isopropoxy-benzyloxy)-3-methyl-phenyl]-acetic acid 
• 64360-44-7 [4-(4-Methoxy-3-methyl-benzyloxy)-3-methyl-phenyl]-acetic acid 

Relevant articles and documents

DDR2 INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS

The present invention relates to compounds of the formula (I) and in particular medicaments comprising at least one compound of the formula (I) for use in the treatment and/or prophylaxis of physiological and/or pathophysiological states in the triggering