64372-69-6

Basic information

• Product Name: 1-(2,3,5-tri-O-acetylpentofuranosyl)-1,2-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
• CAS NO: 64372-69-6
• Molecular Formula: C₁₆H₁₈N₄O₈
• Molecular Weight: 394.3361
• Mol File: 64372-69-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 529.6°C at 760 mmHg
• Flash Point: 274.1°C
• Density: 1.62g/cm³
• Vapor Pressure: 2.65E-11mmHg at 25°C
• Refractive Index: 1.667
• CAS DataBase Reference: 1-(2,3,5-tri-O-acetylpentofuranosyl)-1,2-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,3,5-tri-O-acetylpentofuranosyl)-1,2-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one(64372-69-6)
• EPA Substance Registry System: 1-(2,3,5-tri-O-acetylpentofuranosyl)-1,2-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one(64372-69-6)

Safety Data

• Hazardous Substances Data: 64372-69-6(Hazardous Substances Data)

Usage

Description

1-(2,3,5-tri-O-acetylpentofuranosyl)-1,2-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one is a heterocyclic chemical compound derived from pentofuranose and pyrazolo[3,4-d]pyrimidin-4-one. It features a unique structure with acetylation of the pentofuranose portion, which enhances its stability and solubility. The presence of the pyrazolo[3,4-d]pyrimidin-4-one core, a common motif in bioactive compounds, indicates potential pharmacological properties and biological activity. Further research is necessary to explore its full potential and applications.

Uses

Used in Pharmaceutical Industry:
1-(2,3,5-tri-O-acetylpentofuranosyl)-1,2-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one is used as a potential drug candidate for various therapeutic applications due to its heterocyclic structure and potential pharmacological properties. The acetylation of the pentofuranose portion may contribute to improved stability and solubility, which are crucial factors in drug development.
Used in Chemical Research:
1-(2,3,5-tri-O-acetylpentofuranosyl)-1,2-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one is also used as a subject of study in chemical research to understand its biological activity, interactions with biological targets, and potential applications in the development of new drugs and therapies. The research may lead to the discovery of novel treatments for various diseases and conditions.

Upstream product

• 315-30-0 Allopurinol 
• 51642-61-6 1-(trimethylsilyl)-4-(trimethylsilyloxy)-1H-pyrazolo<3,4-d>pyrimidine 
• 13035-61-5 1,2,3,5-tetraacetylribose 

Downstream Products

• 16220-07-8 allopurinol riboside 
• 78586-33-1 4-chloro-1-(2,3,5-tri-O-acetyl-D-ribofuranosyl)pyrazolo<3,4-d>pyrimidine 
• 78586-40-0 1-β-D-ribofuranosylpyrazolo<3,4-d>pyrimidine 
• 78586-42-2 4-(mercapto-1-methyl-4-nitroimidazol-5-yl)-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)pyrazolo<3,4-d>pyrimidine 
• 78586-43-3 p-benzaldehyde (1-β-D-ribofuranosylpyrazolo<3,4-d>pyrimidin-4-yl)hydrazone 
• 78586-34-2 4-anilino-1-(2,3,5-tri-acetyl-β-D-ribofuranosyl)pyrazolo<3,4-d>pyrimidine 
• 78586-39-7 4-(furfurylamino)-1-(5-O-acetyl-β-D-ribofuranosyl)pyrazolo<3,4-d>pyrimidine 
• 78586-37-5 4-(benzylamino)-1-(5-O-acetyl-β-D-ribofuranosyl)pyrazolo<3,4-d>pyrimidine 
• 78586-35-3 4-anilino-1-β-D-ribofuranosylpyrazolo<3,4-d>pyrimidine 
• 78586-44-4 4-<<(dimethylamino)methylene>amino>-1-(β-D-ribofuranosyl)pyrazolo<3,4-d>pyrimidine 
• 70421-26-0 4-methoxy-1-β-D-ribofuranosylpyrazolo<3,4-d>pyrimidine 
• 78586-38-6 4-(furfurylamino)-1-β-D-ribofuranosylpyrazolo<3,4-d>pyrimidine 
• 64372-76-5 4-hydrazino-1-(β-D-ribofuranosyl)pyrazolo<3,4-d>pyrimidine 
• 64372-75-4 4-(dimethylamino)-1-β-D-ribofuranosylpyrazolo<3,4-d>pyrimidine 

Relevant articles and documents

C4-substituted 1-beta-D-ribofuranosylpyrazolo[3,4-d]pyrimidines as adenosine agonist analogues.

The synthesis of four novel C4-substituted 1-beta-D-ribofuranosylpyrazolo[3,4-d]pyrimidines is reported, and the compounds were examined as adenosine receptor agonist analogues. Neither receptor affinity nor biological activity was as potent as the purine