64481-12-5 Usage
Description
6-Chloro-3-formyl-7-methylchromone, also known as 6-Chloro-7-methyl-4-oxo-4H-1-benzopyran-3-carboxaldehyde, is a benzopyran derivative characterized by its bicyclic heterocyclic structure, which consists of a benzene ring fused to a heterocyclic pyran ring. This molecule is of significant interest due to its potential applications in various fields.
Uses
Used in Pharmaceutical Research:
6-Chloro-3-formyl-7-methylchromone is used as a suitable reagent for studying the multidrug resistance reversal by some 3-formylchromones in human colon cancer and mouse lymphoma cells transfected with the human MDR1 gene. Its application in this field is crucial for understanding and potentially overcoming the challenges posed by multidrug resistance in cancer treatment.
Used in Chemical Synthesis:
In the field of chemical synthesis, 6-Chloro-3-formyl-7-methylchromone serves as a suitable reagent for the synthesis of a uridine-based library. This application highlights its utility in the development of new compounds and molecules with potential biological activities and therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 64481-12-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,4,8 and 1 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 64481-12:
(7*6)+(6*4)+(5*4)+(4*8)+(3*1)+(2*1)+(1*2)=125
125 % 10 = 5
So 64481-12-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H7ClO3/c1-6-2-10-8(3-9(6)12)11(14)7(4-13)5-15-10/h2-5H,1H3
64481-12-5Relevant articles and documents
One pot and metal-free approach to 3-(2-Hydroxybenzoyl)-1-aza-anthraquinones
Yuan, Jiaqi,He, Qian,Song, Shanshan,Zhang, Xiaofei,Miao, Zehong,Yang, Chunhao
supporting information, (2019/08/30)
Herein, a direct strategy to synthesize 3-(2-hydroxybenzoyl)-1-aza-anthraquinones with excellent efficiency,mild conditions, and benign functional group compatibilitywas reported. Avariety of 3-formylchromone compounds were employed as compatible substrates and this protocol gave the 3-(2-hydroxybenzoyl)-1-aza-anthraquinone derivatives in good to excellent yields without inert gas and expensive transition metal catalysts. Some compounds displayed good anti-proliferative activities.
2-Hydroxy Ketones, V. --- Preperation of Substituted Chromones
Cascaval, Alexandru
, p. 669 - 672 (2007/10/02)
Various 2-hydroxyacetophenone derivatives react with Vilsmeier reagent according to the Harnisch method to give the substituted chromones 2b-i, which have been identified by elemental analyses and IR and 1H-NMR spectra.
