64482-27-5

Basic information

• Product Name: Benzoyl chloride, 6-bromo-2,3-dimethoxy-
• CAS NO: 64482-27-5
• Molecular Formula: C9H8BrClO3
• Molecular Weight: 279.518
• Mol File: 64482-27-5.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Benzoyl chloride, 6-bromo-2,3-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 6-bromo-2,3-dimethoxy-(64482-27-5)
• EPA Substance Registry System: Benzoyl chloride, 6-bromo-2,3-dimethoxy-(64482-27-5)

Safety Data

• Hazardous Substances Data: 64482-27-5(Hazardous Substances Data)

Upstream product

• 7150-01-8 2-acetoxy-3-methoxybenzaldehyde 
• 20035-41-0 6-bromo-2-hydroxy-3-methoxybenzaldehyde 
• 53811-50-0 6-bromo-2,3-dimethoxybenzaldehyde 
• 1521-38-6 2,3-dimethoxybenzoic acid 
• 60555-93-3 6-bromo-2,3-dimethoxybenzoic acid 

Downstream Products

• 64482-28-6 2-(6'-bromo-2',3'-dimethoxybenzoyl)-6,7-dimethoxy-1-methylene-1,2,3,4-tetrahydroisoquinoline 
• 185245-95-8 N-(6-bromo-2,3-dimethoxybenzoyl)-6-hydroxy-8,9-methylenedioxy-1,2,3,4,5,6-hexahydro-3-benzazocine 
• 64482-29-7 2-(6'-bromo-2',3'-dimethoxybenzoyl)-1-methylene-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline 
• 169902-69-6 N-<2-(3,4-Methylenedioxyphenyl)ethyl>-N-<2,2-bis(phenylsulfanyl)ethenyl>-6-bromo-2,3-dimethoxybenzamide 
• 187272-11-3 (7-Benzenesulfonyl-6-hydroxy-1,2,4,5,6,7-hexahydro-azocino[5,4-b]indol-3-yl)-(6-bromo-2,3-dimethoxy-phenyl)-methanone 
• 265670-63-1 6-bromo-N-(2,2-dimethoxy-ethyl)-N-(diphenyl-phosphinoylmethyl)-2,3-dimethoxy-benzamide 
• 181634-59-3 6-Bromo-2,3-dimethoxy-N-(6,7-methylenedioxy-1-naphthyl)benzamide 
• 385390-29-4 N-(2-benzo[1,3]dioxol-5-yl-ethyl)-6-bromo-N-(2,2-dimethyl-4H-[1,3]dioxon-5-yl)-2,3-dimethoxy-benzamide 
• 612846-03-4 6-bromo-2,3-dimethoxy-N-(4-methoxybenzyl)benzamide 
• 868051-69-8 7-(6-bromo-2,3-dimethoxy-benzoyl)-6,7,8,9-tetrahydro-1,3-dioxa-7-aza-cyclohepta[f]inden-5-one 
• 876189-26-3 6-bromo-N-(2,2-dimethoxyethyl)-2,3-dimethoxybenzamide 
• 945594-74-1 C₂₀H₁₈BrNO₆ 
• 1235871-85-8 C₃₁H₃₁NO₈ 
• 1235871-62-1 C₂₈H₃₁NO₅ 

Relevant articles and documents

Synthesis of Methoxy-, Methylenedioxy-, Hydroxy-, and Halo-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors and Their Biological Activity for Drug-Resistant Cancer

As a recently discovered DNA repair enzyme, tyrosyl-DNA phosphodiesterase 1 (TDP1) removes topoisomerase IB (TOP1)-mediated DNA protein cross-links. Inhibiting TDP1 can potentiate the cytotoxicity of TOP1 inhibitors and overcome cancer cell resistance to

Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives

Antibiotic resistance has prompted efforts to discover antibiotics with novel mechanisms of action. FtsZ is an essential protein for bacterial cell division, and has been viewed as an attractive target for the development of new antibiotics. Sanguinarine is a benzophenanthridine alkaloid that prevents cytokinesis in bacteria by inhibiting FtsZ self-assembly. In this study, a series of 5-methylbenzo[c]phenanthridinium derivatives were synthesized and evaluated for antibacterial activity against Staphylococcus aureus and Enterococcus faecalis. The data indicate that the presence of a 1- or 12-phenyl substituent on 2,3,8,9-tetramethoxy-5-methylbenzo[c]phenanthridinium chloride significantly enhances antibacterial activity relative to the parent compound or sanguinarine.

Synthesis of isoindolobenzazepine alkaloids based on radical reactions or Pd(0)-catalyzed reactions

(Chemical Equation Presented) Methods for synthesis of a ring system characteristic of isoindolobenzazepine alkaloids were studied. Synthesis of lennoxamine and a formal synthesis of chelenine were accomplished in a short route via radical or Pd(0)-cataly