645-66-9 Usage
Description
Dodecanoic acid,1,1'-anhydride, also known as Dodecanedioic anhydride, is an organic compound derived from the dehydration of two molecules of dodecanoic acid. It is a colorless to pale yellow liquid with a mild, fatty odor. Its chemical structure consists of two dodecanoic acid molecules linked by an anhydride bridge, which provides it with unique chemical properties and reactivity.
Uses
Used in Chemical Conjugation:
Dodecanoic acid,1,1'-anhydride is used as a chemical conjugating agent for the attachment of tumor cell membrane components in carbonate buffer. This application takes advantage of its anhydride reactivity, which allows it to form stable covalent bonds with various functional groups present on the cell membrane, facilitating the development of targeted therapies and diagnostic tools for cancer research.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Dodecanoic acid,1,1'-anhydride is used as a key intermediate in the synthesis of various drug molecules. Its ability to form esters and amides makes it a versatile building block for the development of new pharmaceutical compounds with potential therapeutic applications.
Used in Cosmetics Industry:
Dodecanoic acid,1,1'-anhydride is also utilized in the cosmetics industry as a component in the formulation of various cosmetic products. Its mild, fatty odor and reactivity make it suitable for use in fragrances, creams, and lotions, where it can improve the texture and stability of the final product.
Used in Polymer Synthesis:
In the field of polymer chemistry, Dodecanoic acid,1,1'-anhydride is employed as a monomer or cross-linking agent in the synthesis of polymers with specific properties. Its anhydride functionality allows for the formation of polyesters, polyamides, and other polymeric materials with tailored characteristics for various applications, such as biodegradable plastics and coatings.
Overall, Dodecanoic acid,1,1'-anhydride is a versatile chemical with a wide range of applications across different industries, including pharmaceuticals, cosmetics, and polymer synthesis. Its unique chemical properties and reactivity make it a valuable compound for the development of new products and technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 645-66-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,4 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 645-66:
(5*6)+(4*4)+(3*5)+(2*6)+(1*6)=79
79 % 10 = 9
So 645-66-9 is a valid CAS Registry Number.
InChI:InChI=1/C24H46O3/c1-3-5-7-9-11-13-15-17-19-21-23(25)27-24(26)22-20-18-16-14-12-10-8-6-4-2/h3-22H2,1-2H3
645-66-9Relevant articles and documents
Synthesis of Succinic Gemini Surfactants and the Effect of Stereochemistry on Their Monolayer Behaviors
Kawase, Tokuzo,Kagawa-Ohara, Maiko,Aisaka, Tsunetomo,Oida, Tatsuo
, p. 615 - 627 (2015)
In this work, succinic gemini surfactants, dl- and meso-2,3-bis(alkyl)succinic acids (alkyl: C6H13-C13H27), were successfully synthesized by oxidative coupling of enolates of fatty acid tert-butyl esters with copper(II) bromide followed by treatment with CF3COOH. Focusing on the influence of stereochemistry (dl- and meso-) of succinic geminis, their monolayer behaviors at the air-water interface were explored using surface pressure-area (Π-A) isotherms, the compression modulus of monolayers (εs), and Brewster angle microscope (BAM) analysis. meso-2,3-Bis(undecyl)succinic acid showed a unique isotherm where the surface pressure drastically decreased at A = ~0.56 nm2 (Π = 21.9 mN m-1) regardless of compression rates and subphase temperatures, while dl-isomer showed the common isotherm of gas → liquid-expanded → liquid-condensed phase transitions. BAM analysis on meso-2,3-bis(undecyl)succinic acid films at the air-water interface showed that small islands of aggregates appear just after the maximum pressure (A = ~0.56 nm2), and on further compression needle-shaped assemblies appear that can grow in size. It was reasonably concluded that hydrophobic interactions can operate more effectively in meso-isomers than in dl-isomers, and that meso-molecules can "jump up" to cause a transition from monolayer to bilayer. This is the first finding of the "jumping-up" phenomenon of gemini surfactants having meso-stereochemistry.
Nickel catalyzed decarboxylative alkylation of aryl triflates with anhydrides
Chen, Hui,Liao, Xuebin
, p. 4186 - 4191 (2019/06/18)
Aliphatic acid anhydrides are the versatile building blocks and the new method for the conversion of anhydrides is thus of great significance. Herein, we report the decarboxylative alkylation of aryl triflates with aliphatic acid anhydrides via nickel catalysis. This novel method provides a facile access to construct Csp2-Csp3 bond. In addition, this method is compatible with a broad array of functional groups and exhibits good substrates scope.
Synthesis of symmetric anhydrides using visible light-mediated photoredox catalysis
Konieczynska, Marlena D.,Dai, Chunhui,Stephenson, Corey R. J.
supporting information; experimental part, p. 4509 - 4511 (2012/07/31)
A new approach to anhydride formation is reported via activation of C-O bonds by the Vilsmeier-Haack reagent formed by Ru(bpy)3Cl2 and CBr4 in DMF. Various aryl and alkyl carboxylic acids are converted to the corresponding anhydrides in excellent yields.