645387-45-7

Basic information

• Product Name: (3R,4R)-3,4-diphenyl-2,5-diazabicyclo[4.2.0]oct-1⁽⁶⁾-ene-7,8-dione
• Synonyms: (3R,4R)-3,4-diphenyl-2,5-diazabicyclo[4.2.0]oct-1⁽⁶⁾-ene-7,8-dione
• CAS NO: 645387-45-7
• Molecular Weight: 290.321
• Mol File: 645387-45-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,4R)-3,4-diphenyl-2,5-diazabicyclo[4.2.0]oct-1⁽⁶⁾-ene-7,8-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R)-3,4-diphenyl-2,5-diazabicyclo[4.2.0]oct-1⁽⁶⁾-ene-7,8-dione(645387-45-7)
• EPA Substance Registry System: (3R,4R)-3,4-diphenyl-2,5-diazabicyclo[4.2.0]oct-1⁽⁶⁾-ene-7,8-dione(645387-45-7)

Safety Data

• Hazardous Substances Data: 645387-45-7(Hazardous Substances Data)

Upstream product

• 35132-20-8 (R,R)-1,2-diphenylethylenediamine 
• 5231-87-8 3,4-diethoxy-3-cyclobuten-1,2-dione 
• 2892-62-8 3,4-dibutoxy-3-cyclobutene-1,2-dione 

Downstream Products

• 1255088-69-7 (3R,4R)-2,5-di-n-pentyl-3,4-diphenyl-2,5-diazabicyclo[4.2.0]oct-1⁽⁶⁾-ene-7,8-dione 
• 1255088-70-0 (3R,4R)-2,5-dibenzyl-3,4-diphenyl-2,5-diazabicyclo[4.2.0]oct-1⁽⁶⁾-ene-7,8-dione 
• 1255088-68-6 (3R,4R)-2,5-diisopropyl-3,4-diphenyl-2,5-diazabicyclo[4.2.0]oct-1⁽⁶⁾-ene-7,8-dione 
• 1255088-67-5 (3R,4R)-2,5-dimethyl-3,4-diphenyl-2,5-diazabicyclo[4.2.0]oct-1⁽⁶⁾-ene-7,8-dione 

Relevant articles and documents

Synthesis and structural features of chiral cyclic squaramides and their application in asymmetric catalytic reaction

We report the synthesis and structural elucidation of two series of chiral cyclic squaramides, i.e. six-and twelve-membered ring squaramides 4 and 6, based on the cyclobutenedione structure, containing enantiomerically pure (1R,2R)-1,2-diphenylethylenediamine as the chiral element. Compounds 4a-d obtained from alkylation of 3, crystallize in space groups of monoclinic P2 1, monoclinic P21, monoclinic chiral P212 121, and the orthorhombic C2221, respectively. For the first time the crystal structures of six-membered ring chiral cyclic squaramides are reported. These novel ligands have been tested in the enantioselective addition of diethylzinc to aryl aldehydes to give the corresponding alcohols in moderate yields, albeit with low enantioselectivity. ARKAT-USA, Inc.