64605-36-3

Basic information

• Product Name: Ethanone, 1-(2-amino-5-chlorophenyl)-2-chloro- (9CI)
• Synonyms: Ethanone, 1-(2-amino-5-chlorophenyl)-2-chloro- (9CI)
• CAS NO: 64605-36-3
• Molecular Formula: C₈H₇Cl₂NO
• Molecular Weight: 204.05328
• Product Categories: ACETYLHALIDE
• Mol File: 64605-36-3.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethanone, 1-(2-amino-5-chlorophenyl)-2-chloro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2-amino-5-chlorophenyl)-2-chloro- (9CI)(64605-36-3)
• EPA Substance Registry System: Ethanone, 1-(2-amino-5-chlorophenyl)-2-chloro- (9CI)(64605-36-3)

Safety Data

• Hazardous Substances Data: 64605-36-3(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(2-amino-5-chlorophenyl)-2-chloro- (9CI) is a chemical compound that belongs to the ketone group and is characterized by the presence of an amino group, a chlorine atom, and a phenyl ring. It is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various medications. Ethanone, 1-(2-amino-5-chlorophenyl)-2-chloro- (9CI) has potential applications in the development of antimicrobial agents, pharmaceuticals, and agrochemicals due to its unique chemical structure and properties. However, further research is needed to fully understand its potential uses and effects.

Upstream product

• 106-47-8 4-chloro-aniline 
• 894095-04-6 ketimine of 5-chloro-2-amino-α-chloroacetophenone 
• 107-14-2 chloroacetonitrile 

Downstream Products

• 227803-35-2 5-chloro-3-(phenylthio)-1H-indole 

Relevant articles and documents

Synergistic Cooperative Effect of Sodium borohydride-Iodine Towards Cascade C?N and C?S/Se Bond Formation: One-pot Regioselective Synthesis of 3-Sulfenyl/selenyl Indoles and Mechanistic Insight

In this work, a new strategy to synthesize 3-sulfenyl/selenyl indole is reported wherein LC?MS reveals a novel insight into synergistic cooperative effect of NaBH4-I2 which allows cascade C?N and C?S/C?Se bond formations via reduction-nucleophilic cyclization-chalcogenylation, three steps in one-pot, towards regioselective synthesis of diverse 3-chalcogenyl indoles including 5-bromo-3-[(3,4,5-trimethoxyphenyl)thio]-1H-indole, a known lead anticancer compound, directly from 2-amino-phenacylchlorides and thiophenols or disulfides/diselenides in aqueous dioxane under transition-metal-free condition. (Figure presented.).

PYRAZOLOPYRIDINE PYRAZOLOPYRIMIDINE AND RELATED COMPOUNDS

In one aspect this invention relates generally to compounds of Formula: and sub-formulas thereof, or a tautomer of each thereof, a pharmaceutically acceptable salt of each thereof, or a pharmaceutically acceptable solvate of each of the foregoing, where X1, L1, L3, and R3 are described herein.

5-MEMBERED HETEROARYLCARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS

The invention relates to a compound of the formula (I) in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.