646057-80-9

Basic information

• Product Name: H-Pro-Phe-Asn-{Ser(Bn)-Leu}-Ala-Ile-OH
• Synonyms: H-Pro-Phe-Asn-{Ser(Bn)-Leu}-Ala-Ile-OH
• CAS NO: 646057-80-9
• Molecular Weight: 893.05
• Mol File: 646057-80-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: H-Pro-Phe-Asn-{Ser(Bn)-Leu}-Ala-Ile-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-Pro-Phe-Asn-{Ser(Bn)-Leu}-Ala-Ile-OH(646057-80-9)
• EPA Substance Registry System: H-Pro-Phe-Asn-{Ser(Bn)-Leu}-Ala-Ile-OH(646057-80-9)

Safety Data

• Hazardous Substances Data: 646057-80-9(Hazardous Substances Data)

Upstream product

• 646057-70-7 (3S,4S,5R)-5-benzyloxy-N-[(1S)-1-(tert-butoxycarbonyl)-3-methylbutyl]-3-(9-fluorenylmethoxycarbonylamino)-4-hydroxypiperidin-2-one 
• 239784-28-2 (3S,4S,5R)-3-amino-5-benzyloxy-N-[(1S)-1-(tert-butoxycarbonyl)-3-methylbutyl]-4-hydroxypiperidin-2-one 
• 35661-39-3 N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine 
• 35661-40-6 N-Fmoc L-Phe 
• 132388-59-1 L-Asn(Trt) 
• 646057-74-1 2(S)-2-[(3R,4S,5R)-5-benzyloxy-3-(fluorenyloxycarbonylamino)-4-hydroxy-2-oxo-1-piperidinyl]isohexanoic acid 

Downstream Products

• 646057-85-4 epi-benzyl-ψ-stylostatin 
• 646057-84-3 benzyl-ψ-stylostatin 

Relevant articles and documents

Constrained Derivatives of Stylostatin 1. 1. Synthesis and Biological Evaluation as Potential Anticancer Agents

Hydroxyaminolactams have been used as constrained surrogates of the Ser-Leu dipeptide in the synthesis of analogues of the cycloheptapeptide stylostatin 1 (2). The rate of cyclization through formation of the Ile-Pro amide bond allowed us to prove that th