6462-31-3

Basic information

• Product Name: Benzene, 1,3,5-trimethyl-2-(methylsulfonyl)-
• CAS NO: 6462-31-3
• Molecular Formula: C10H14O2S
• Molecular Weight: 198.286
• Mol File: 6462-31-3.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzene, 1,3,5-trimethyl-2-(methylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,3,5-trimethyl-2-(methylsulfonyl)-(6462-31-3)
• EPA Substance Registry System: Benzene, 1,3,5-trimethyl-2-(methylsulfonyl)-(6462-31-3)

Safety Data

• Hazardous Substances Data: 6462-31-3(Hazardous Substances Data)

Upstream product

• 7570-91-4 methyl mesityl sulphide 
• 59057-35-1 2,4,6-trimethylbenzenesulphinic acid 
• 124-63-0 methanesulfonyl chloride 
• 108-67-8 1,3,5-trimethyl-benzene 
• 1912-32-9 n-butyl methanesulfonate 
• 16182-15-3 2,4,6-trimethylbenzenesulfonohydrazide 
• 868-85-9 Dimethyl phosphite 
• 1541-10-2 mesitylthiol 
• 75-75-2 methanesulfonic acid 
• 7143-01-3 Methanesulfonic anhydride 
• 1077-62-9 SnMe₃(C₆H₂Me₃-2,4,6) 
• 558-25-8 methyl fluorosulfonate 
• 41138-92-5 methanesulfonyl bromide 

Downstream Products

• 21134-15-6 1-(4-(methylsulfonyl)phenoxy]benzene 
• 47189-05-9 1-phenoxy-4-(phenylsulfonyl)benzene 
• 3517-90-6 p-anisyl methyl sulfone 
• 3112-84-3 4-methoxyphenyl phenyl sulfone 
• 108-67-8 1,3,5-trimethyl-benzene 
• 510730-03-7 1-(2,4,6-trimethylphenylsulfonyl)-5-hexen-2-one 
• 510730-06-0 5-methyl-1-(2,4,6-trimethylphenylsulfonyl)-5-hexen-2-one 
• 510730-14-0 6-methyl-1-(2,4,6-trimethylphenylsulfonyl)-5-hepten-2-one 
• 510730-11-7 5-bromo-1-(2,4,6-trimethylphenylsulfonyl)-5-hexen-2-one 
• 1015073-34-3 C₃₂H₄₀O₄SSi 
• 510730-34-4 1-[3-diazo-2-oxo-3-(2,4,6-trimethylphenylsulfonyl)propyl]-1-methyl-2,5-cyclohexadiene 
• 510730-12-8 5-bromo-1-diazo-1-(2,4,6-trimethylphenylsulfonyl)-5-hexen-2-one 
• 510730-07-1 1-diazo-5-methyl-1-(2,4,6-trimethylphenylsulfonyl)-5-hexen-2-one 
• 510730-15-1 1-diazo-6-methyl-1-(2,4,6-trimethylphenylsulfonyl)-5-hepten-2-one 

Relevant articles and documents

High Chemoselectivity in the Construction of Aryl Methyl Sulfones via an Unexpected C-S Bond Formation between Sulfonylhydrazides and Dimethyl Phosphite

A highly chemoselective route to aryl methyl sulfones via an unexpected C S bond formation between sulfonylhydrazides and dimethyl phosphite catalyzed by NaI under mild conditions has been established. This transformation provides an alternative and metal-free pathway to acquire various aryl methyl sulfones in good to excellent yields. Notably, dimethyl phosphite was employed as a stable and readily available alkyl source.

Rapid and mild sulfonylation of aromatic compounds with sulfonic acids via mixed anhydrides using Tf2O

An efficient and direct sulfonylation of aromatic compounds with sulfonic acids is described via mixed anhydrides in short reaction times using Tf2O in nitromethane at room temperature.

Investigations on the iron-catalyzed asymmetric sulfide oxidation

The development of an enantioselective sulfide oxidation involving a chiral iron catalyst and aqueous hydrogen peroxide as oxidant is described. In the presence of a simple carboxylic acid, or a carboxylate salt, the reaction affords sulfoxides with remarkable enantioselectivities (up to 96% ee) in moderate to good yields. The influence of the structure of the additive on the reaction outcome is reported. In the sulfoxide-to-sulfone oxidation a kinetic resolution (with s = 4.8) occurs, which, however, plays only a negligible role in the overall enantioselective process. Furthermore, a positive nonlinear relationship between the ee of the product and that of the catalyst has been found. On the basis of these observations, a possible catalyst structure is proposed.