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64691-57-2

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64691-57-2 Usage

General Description

Cyclodextrin-benzaldehyde is a chemical compound formed by the union of cyclodextrin, a cyclic oligosaccharide, with benzaldehyde, an organic compound commonly used in fragrances and flavorings. This complex has been studied for its potential as a drug delivery system due to the ability of cyclodextrin to encapsulate hydrophobic molecules like benzaldehyde. The inclusion of benzaldehyde also imparts unique properties to cyclodextrin, such as enhanced solubility, stability, and bioavailability of the encapsulated drug. As a result, cyclodextrin-benzaldehyde has shown promise in pharmaceutical applications as a carrier for improving the delivery and effectiveness of various drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 64691-57-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,6,9 and 1 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 64691-57:
(7*6)+(6*4)+(5*6)+(4*9)+(3*1)+(2*5)+(1*7)=152
152 % 10 = 2
So 64691-57-2 is a valid CAS Registry Number.
InChI:InChI=1/C42H70O35.C7H6O/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51;8-6-7-4-2-1-3-5-7/h8-63H,1-7H2;1-6H/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-;/m1./s1

64691-57-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name benzaldehyde/β-CyD complex (1:1)

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:64691-57-2 SDS

64691-57-2Synthetic route

benzaldehyde
100-52-7

benzaldehyde

β‐cyclodextrin
7585-39-9

β‐cyclodextrin

benzaldehyde/β-CyD complex (1:1)
64691-57-2

benzaldehyde/β-CyD complex (1:1)

Conditions
ConditionsYield
In d(4)-methanol; water-d2 at 25℃; Equilibrium constant;
acrylonitrile
107-13-1

acrylonitrile

benzaldehyde/β-CyD complex (1:1)
64691-57-2

benzaldehyde/β-CyD complex (1:1)

2-(1-hydroxybenzyl)acrylonitrile
19362-96-0

2-(1-hydroxybenzyl)acrylonitrile

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane for 1h; Condensation; Baylis-Hillman reaction;70%
benzaldehyde/β-CyD complex (1:1)
64691-57-2

benzaldehyde/β-CyD complex (1:1)

A

benzaldehyde
100-52-7

benzaldehyde

B

β‐cyclodextrin
7585-39-9

β‐cyclodextrin

Conditions
ConditionsYield
In d(4)-methanol; water-d2 at 25℃; Equilibrium constant;

64691-57-2Relevant articles and documents

Preparation of α-hydroxyphenylacetic acid with cyclodextrins as an effective phase-transfer catalyst and its reaction mechanism

Tian, Bing Ren,Zhang, Rui Xia,Chu, Hui Min,Huang, Qing,Wang, Zhi Zhong

, p. 359 - 368 (2019)

An effective procedure for the synthesis of α-hydroxyphenylacetic acid with cyclodextrin (CD) catalysts was developed. The phase-transfer catalyst types, catalyst loadings, reaction times, reaction temperatures, and substrate molar ratios were investigated to optimize the reaction conditions. In addition, the factors that affect the reaction were studied, and the relationship between benzaldehyde and β-cyclodextrin (β-CD) was analyzed through 2D-ROESY. The equilibrium constant when β-CD was used as the catalyst was calculated. The results indicated that β-CD is the optimal catalyst for the reported reaction (yield: 69.08%). Furthermore, the mechanism underlying the reported reaction was proposed.

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