64724-49-8

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Basic information

Product Name: Acetamide, N-(4-hydroxy-9H-fluoren-2-yl)-
Synonyms:
CAS NO:64724-49-8
Molecular Formula: C15H13NO2
Molecular Weight: 239.274
EINECS: N/A
Product Categories: N/A
Mol File: 64724-49-8.mol
Article Data: 2

Chemical Properties

Melting Point: 270-272.5 °C (decomp)(Solv: methanol (67-56-1); water (7732-18-5))
Boiling Point: 535.0±50.0 °C(Predicted)
Flash Point: N/A
Appearance: N/A
Density: 1.330±0.06 g/cm3(Predicted)
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Acetamide, N-(4-hydroxy-9H-fluoren-2-yl)-(CAS DataBase Reference)
NIST Chemistry Reference: Acetamide, N-(4-hydroxy-9H-fluoren-2-yl)-(64724-49-8)
EPA Substance Registry System: Acetamide, N-(4-hydroxy-9H-fluoren-2-yl)-(64724-49-8)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 64724-49-8(Hazardous Substances Data)

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64724-49-8 Usage

Description

Acetamide, N-(4-hydroxy-9H-fluoren-2-yl)is a liver produced metabolite of the carcinogen 2-acetamidofluorene (A158535). It can be activated by liver homogenate and has the potential to form potent frameshift mutagens.

Uses

Used in Toxicology Research:
Acetamide, N-(4-hydroxy-9H-fluoren-2-yl)is used as a research compound in toxicology studies for understanding the metabolic activation and mutagenicity of carcinogens. Its role in the formation of potent frameshift mutagens provides valuable insights into the mechanisms of carcinogenesis and the development of potential cancer therapies.
Used in Drug Metabolism Studies:
Acetamide, N-(4-hydroxy-9H-fluoren-2-yl)is used as a model compound in drug metabolism studies to investigate the biotransformation of xenobiotics in the liver. Understanding its metabolic pathways can help in the design of safer and more effective drugs with reduced toxic side effects.
Used in Environmental Monitoring:
Acetamide, N-(4-hydroxy-9H-fluoren-2-yl)can be used as a biomarker for monitoring environmental exposure to carcinogens. Its detection in biological samples can indicate the presence of harmful substances and help in assessing the risk of cancer in exposed populations.

Check Digit Verification of cas no

The CAS Registry Mumber 64724-49-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,7,2 and 4 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 64724-49:
(7*6)+(6*4)+(5*7)+(4*2)+(3*4)+(2*4)+(1*9)=138
138 % 10 = 8
So 64724-49-8 is a valid CAS Registry Number.

64724-49-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	N-(4-hydroxy-9H-fluoren-2-yl)acetamide

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:64724-49-8 SDS

64724-49-8Upstream product

138235-69-5 N-(Sulfonatooxy)-2-(acetylamino)fluorene

64724-49-8Downstream Products

64724-49-8Relevant articles and documents

Hydrolysis kinetics of the ultimate hepatacarcinogen N-(sulfonatooxy)(-2-(acetylamino)fluorene: Detection of long-lived hydrolysis intermediates

Panda,Novak,Magonski

, p. 4524 - 4525 (1989)

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