6486-93-7 Usage
Description
1,2,5-Trihydroxyanthraquinone is an organic compound characterized by the presence of three hydroxyl groups attached to an anthraquinone molecule. It exhibits a dark purplish-red color when combined with aluminum and a dark purplish-red color when combined with chromium. 1,2,5-TRIHYDROXYANTHRAQUINONE is soluble in ethanol and glacial acetic acid, and it displays unique color changes when interacting with concentrated sulfuric acid and boric acid.
Uses
Used in Textile Industry:
1,2,5-Trihydroxyanthraquinone is used as a dye for textiles, particularly for cotton, due to its ability to produce a range of colors depending on the metal ions it interacts with. Its light fastness, ironing fastness, and perspiration fastness make it suitable for various applications in the textile industry.
Used in Chemical Industry:
1,2,5-Trihydroxyanthraquinone is used as an intermediate in the synthesis of various organic compounds and dyes. Its unique chemical properties, such as its solubility in ethanol and glacial acetic acid, make it a valuable component in the development of new chemical products.
Used in Analytical Chemistry:
1,2,5-Trihydroxyanthraquinone is used as a reagent in analytical chemistry for the detection and quantification of certain metal ions, such as aluminum and chromium, due to its color-changing properties when interacting with these ions. This makes it a useful tool for environmental and industrial monitoring.
Preparation
(a) in the presence of ?Boric acid, with fuming sulfuric acid oxidation 1,2-Dihydroxyanthracene-9,10-dione , and hydrolysis; (b) 5,6-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-1-sulfonic acid?and sodium hydroxide reaction; (c) 1,5-Dihydroxyanthracene-9,10-dione with Sodium nitrate and Sodium hydroxide or had better use Sodium hydroxide and Potassium hydroxide mixture for oxidation.
Alkali
Acid
Check Digit Verification of cas no
The CAS Registry Mumber 6486-93-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,4,8 and 6 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6486-93:
(6*6)+(5*4)+(4*8)+(3*6)+(2*9)+(1*3)=127
127 % 10 = 7
So 6486-93-7 is a valid CAS Registry Number.
InChI:InChI=1/C14H8O5/c15-8-3-1-2-6-10(8)12(17)7-4-5-9(16)14(19)11(7)13(6)18/h1-5,15-16,19H
6486-93-7Relevant articles and documents
Synthesis and activity of substituted anthraquinones against a human filarial parasite, Brugia malayi
Dhananjeyan, Mugunthu R.,Milev, Youli P.,Kron, Michael A.,Nair, Muraleedharan G.
, p. 2822 - 2830 (2007/10/03)
Lymphatic filariasis (elephantiasis) is a global public health problem caused by the parasitic nematodes Wuchereria bancrofti and Brugia malayi. We have previously reported anthraquinones from daylily roots with potent activity against pathogenic trematode Schistosoma mansoni. Here we report the synthesis of novel anthraquinones A-S and their antifilrarial activity. Anthraquinones A-S were synthesized by a single-step Friedel-Crafts acylation reaction between phthalic anhydrides and substituted benzenes. The antifilarial properties of these synthetic anthraquinones were tested against microfilaria as well as adult male and female worms of B. malayi. The most active anthraquinone was K, which showed 100% mortality within 1, 5, and 3 days, respectively, against microfilaria and adult male and female worms at 5 ppm concentration. Albendazole, an oral drug currently used to treat parasitic infections, was used as a positive control. Methylated products of anthraquinones did not affect the microfilaria. Histological examination of treated adult female parasites showed most of the anthraquinones caused marked effects on intrauterine embryos.
