648905-80-0

Basic information

• Product Name: Methanone, (2,6-dimethoxy-1-naphthalenyl)[4-[2-(1-piperidinyl)ethoxy]phenyl]-
• CAS NO: 648905-80-0
• Molecular Formula: C26H29NO4
• Molecular Weight: 419.521
• Mol File: 648905-80-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Methanone, (2,6-dimethoxy-1-naphthalenyl)[4-[2-(1-piperidinyl)ethoxy]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2,6-dimethoxy-1-naphthalenyl)[4-[2-(1-piperidinyl)ethoxy]phenyl]-(648905-80-0)
• EPA Substance Registry System: Methanone, (2,6-dimethoxy-1-naphthalenyl)[4-[2-(1-piperidinyl)ethoxy]phenyl]-(648905-80-0)

Safety Data

• Hazardous Substances Data: 648905-80-0(Hazardous Substances Data)

Upstream product

• 5486-55-5 2,6-dimethoxylnaphthalene 
• 166975-76-4 4-(2-(piperidin-1-yl)ethoxy)benzoyl chloride 

Downstream Products

• 648905-79-7 trifluoro-methanesulfonic acid 6-methoxy-1-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-naphthalen-2-yl ester 
• 648905-83-3 [2-(4-methanesulfonylphenyl)-6-methoxynaphthalen-1-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanol 
• 648905-81-1 [2-(4-methanesulfonylphenyl)-6-methoxynaphthalen-1-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone 
• 648905-84-4 [2-(4-methanesulfonylphenyl)-6-methoxynaphthalen-1-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methane 
• 736926-06-0 6-(4-methanesulfonylphenyl)-5-[4-(2-piperidin-1-ylethoxy)benzyl]naphthalen-2-ol 
• 649724-98-1 (2-hydroxy-6-methoxy-naphthalen-1-yl)-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone 

Relevant articles and documents

A selective estrogen receptor modulator designed for the treatment of uterine leiomyoma with unique tissue specificity for uterus and ovaries in rats

The design of a novel selective estrogen receptor modulator (SERM) for the potential treatment of uterine leiomyoma is described. 16 (LY2066948-HCl) binds with high affinity to estrogen receptors α and β (ERα and ERβ, respectively) and is a potent uterine

SELECTIVE ESTROGEN RECEPTOR MODULATORS

The present invention relates to a selective estrogen receptor modulators of formula I (I); or a pharmaceutical acid addition salt thereof; and of formula II (II); or a pharmaceutical salt thereof; useful, e.g., for treating endometriosis and/or uterine leiomyoma/leiomyomata.

DERIVATIVE OF DIHYDRO-DIBENZO (A) ANTHRACENES AND THEIR USE AS SELECTIVE ESTROGEN RECEPTOR MODULATORS

The present invention provides a compound of the formula (I) wherein R1 is -H, -OH, -O(C1-C4 alkyl), -OCOC6H5, -OCO(C1-C6 alkyl), or -OSO2(C2-C6