649736-47-0

Basic information

• Product Name: 4-Fluoro-2-methyl-5-(phenylmethoxy)-1H-indole
• Synonyms: 4-Fluoro-2-methyl-5-(phenylmethoxy)-1H-indole;5-(benzyloxy)-4-fluoro-2-Methyl-1H-indole
• CAS NO: 649736-47-0
• Molecular Formula: C16H14FNO
• Molecular Weight: 255
• Mol File: 649736-47-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 429.349 °C at 760 mmHg
• Flash Point: 213.463 °C
• Appearance: /
• Density: 1.232
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: 4-Fluoro-2-methyl-5-(phenylmethoxy)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Fluoro-2-methyl-5-(phenylmethoxy)-1H-indole(649736-47-0)
• EPA Substance Registry System: 4-Fluoro-2-methyl-5-(phenylmethoxy)-1H-indole(649736-47-0)

Safety Data

• Hazardous Substances Data: 649736-47-0(Hazardous Substances Data)

Usage

Description

4-Fluoro-2-methyl-5-(phenylmethoxy)-1H-indole is a chemical compound with the molecular formula C17H14FNO. It is an indole derivative characterized by the presence of a fluorine atom at the 4 position, a methyl group at the 2 position, and a phenylmethoxy group at the 5 position. 4-Fluoro-2-methyl-5-(phenylmethoxy)-1H-indole is commonly utilized in organic synthesis and pharmaceutical research, and it may have potential applications in the development of new pharmaceutical drugs or as a precursor in the synthesis of other organic compounds. Furthermore, it may exhibit intriguing biological activities that merit further exploration.

Uses

Used in Pharmaceutical Research:
4-Fluoro-2-methyl-5-(phenylmethoxy)-1H-indole is used as a research compound for the development of new pharmaceutical drugs due to its unique structural features and potential biological activities. Its indole moiety and substituents may contribute to its interaction with various biological targets, making it a valuable candidate for drug discovery.
Used in Organic Synthesis:
In the field of organic synthesis, 4-Fluoro-2-methyl-5-(phenylmethoxy)-1H-indole serves as a precursor for the synthesis of other organic compounds. Its versatile structure allows for further functionalization and modification, enabling the creation of a wide range of chemical entities with diverse properties and applications.
Used in Biological Activity Studies:
4-Fluoro-2-methyl-5-(phenylmethoxy)-1H-indole is used as a subject of biological activity studies to explore its potential effects on various biological systems. Its unique structure may confer specific interactions with cellular components or signaling pathways, offering insights into its therapeutic potential and mechanisms of action.
Used in Chemical Libraries:
4-Fluoro-2-methyl-5-(phenylmethoxy)-1H-indole is also utilized in the construction of chemical libraries for high-throughput screening. Its inclusion in such libraries facilitates the identification of novel bioactive molecules and the elucidation of structure-activity relationships, which are crucial for the advancement of drug discovery efforts.

InChI:InChI=1/C16H14FNO/c1-11-9-13-14(18-11)7-8-15(16(13)17)19-10-12-5-3-2-4-6-12/h2-9,18H,10H2,1H3

Upstream product

• 288385-98-8 1-(3-benzyloxy-2-fluoro-6-nitro-phenyl)-propan-2-one 

Relevant articles and documents

PROCESS FOR PREPARING CERTAIN PYRROLOTRIAZINE COMPOUNDS

The present invention relates to a process for preparing certain pyrrolotriazine compounds of the formula (I) and pharmaceutically acceptable salts thereof. The formula (I) compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.