6502-39-2 Usage
Description
(2E)-4-(furan-2-yl)-N-hydroxybut-3-en-2-imine, commonly known as Furoxan, is a nitrogen-containing heterocyclic compound with a furan ring and an oxime functional group. This unique structure endows it with high reactivity and potential applications in various fields due to its ability to release nitric oxide (NO).
Uses
Used in Pharmaceutical Industry:
(2E)-4-(furan-2-yl)-N-hydroxybut-3-en-2-imine is used as a potential vasodilator and antiplatelet agent for its ability to release nitric oxide, which aids in relaxing blood vessels and preventing blood clot formation. This makes it a candidate for the treatment of cardiovascular diseases.
Used in Antibacterial Applications:
In the field of antimicrobial research, (2E)-4-(furan-2-yl)-N-hydroxybut-3-en-2-imine is used as a potential antibacterial agent. Its NO-releasing property contributes to its effectiveness against certain bacteria, suggesting a possible role in combating infections.
Used in Anticancer Applications:
(2E)-4-(furan-2-yl)-N-hydroxybut-3-en-2-imine is also being investigated for its potential as an anticancer agent. (2E)-4-(furan-2-yl)-N-hydroxybut-3-en-2-imine's ability to release nitric oxide has been linked to anti-tumor and anti-inflammatory effects, making it a subject of interest for cancer treatment research.
However, it is important to note that the reactivity and potential toxicity of (2E)-4-(furan-2-yl)-N-hydroxybut-3-en-2-imine require further studies to establish its safety and efficacy for medicinal purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 6502-39-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,5,0 and 2 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 6502-39:
(6*6)+(5*5)+(4*0)+(3*2)+(2*3)+(1*9)=82
82 % 10 = 2
So 6502-39-2 is a valid CAS Registry Number.
6502-39-2Relevant articles and documents
Polysubstituted Indole Synthesis via Palladium/Norbornene Cooperative Catalysis of Oxime Esters
Liu, Jiechun,Lin, Haojiang,Jiang, Huanfeng,Huang, Liangbin
, p. 484 - 489 (2022/01/20)
Polysubstituted indoles are prevalent in pharmaceuticals, agrochemicals, and organic materials. Presented herein is the fact that polyfunctionalized indoles can be efficiently constructed from easily accessible oxime esters and aryl iodides, involving a palladium/norbornene synergistic synthesis. The reaction is enabled by a unique class of electrophiles in palladium/norbornene cooperative catalysis, which are oxime esters derived from simple ketone. The broad substrate scope and high functional group tolerance could make this method attractive for the synthesis of polysubstituted indoles.
