65079-19-8Relevant articles and documents
Synthesis of 4,7-phenanthroline methyl derivatives
Gusak,Tereshko,Kozlov
, p. 1662 - 1668 (2004)
6-Aminoquinaldine condensation with aromatic aldehydes and cyclic β-diketones (1,3-cyclohexanedione or dimedone) in butanol afforded new 12-aryl-3-methyl-8,9,10,12-tetrahydro-7H-benzo[b][4,7]phenanthrolin-11-ones and their 9,9-dimethyl derivatives. 2004 MAIK "Nauka/ Interperiodica".
Synthesis and biological evaluation of 2-quinolineacrylamides
Chen, Mei-Chuan,Chen, Shiou-Sheng,Hsu, Fu-Chun,Lee, Hsueh-Yun,Lin, Mei-Hsiang,Liou, Jing-Ping,Liu, Yi-Ting,Wang, Shih-Wei
, (2020/01/11)
A series of C6-substituted N-hydroxy-2-quinolineacrylamides (3–15), with four types of bridging groups have been synthesized. Most of these compounds exhibit antiproliferative activity against A549 and HCT116 cells and Western blot analysis revealed that they are able to inhibit HDAC. Measurement of the HDAC isoform activity of ether-containing compounds showed that compound 9 has distinct HDAC6 selectivity, more than 300-fold over other isoforms. This paper describes the development of 6-aryloxy-N-hydroxy-2-quinolineacrylamides as potential HDAC6 inhibitors.
Insight into the effects of modifying chromophores on the performance of quinoline-based dye-sensitized solar cells
Mao, Mao,Wang, Jian-Bo,Liu, Xiu-Lin,Wu, Guo-Hua,Fang, Xia-Qin,Song, Qin-Hua
, p. 23 - 32 (2017/09/12)
A series of organic dyes based on quinoline as an electron-deficient π-linker, were designed and synthesized for dye sensitized solar cells (DSSC) application. These push-pull conjugated dyes, sharing same anchoring group with distinctive electron-rich donating groups such as N,N-diethyl (DEA-Q), 3,6-dimethoxy carbazole (CBZ-Q), bis(4-butoxyphenyl)amine (BPA-Q), were synthesized by Riley oxidation of [sbnd]CH3 followed by Knoevenagel condensation of the corresponding aldehyde precursors 2a–c with cyanoacrylic acid. The optical, electrochemical, theoretical calculation and photovoltaic properties with these three dyes were systematically investigated. Compared to DEA-Q and CBZ-Q, BPA-Q possesses better light harvesting properties with regard to extended conjugate length, red-shifted intramolecular charge transfer band absorption and broaden light-responsive IPCE spectrum, resulting in a greater short circuit photocurrent density output. BPA-Q also has improved open-circuit voltage due to the apparent large charge recombination resistance. Consequently, assembled with iodine redox electrolytes, the device with BPA-Q achieved the best overall conversion efficiency value of 3.07% among three dyes under AM 1.5G standard conditions. This present investigation demonstrates the importance of various N-substituent chromophores in the prevalent D-π-A type organic sensitizers for tuning the photovoltaic performance of their DSSCs.
