65127-72-2

Basic information

• Product Name: Benzene, 1,4-bis(bromoethynyl)-
• CAS NO: 65127-72-2
• Molecular Formula: C10H4Br2
• Molecular Weight: 283.95
• Mol File: 65127-72-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzene, 1,4-bis(bromoethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,4-bis(bromoethynyl)-(65127-72-2)
• EPA Substance Registry System: Benzene, 1,4-bis(bromoethynyl)-(65127-72-2)

Safety Data

• Hazardous Substances Data: 65127-72-2(Hazardous Substances Data)

Upstream product

• 937-65-5 Bromdiethinyl-benzol 
• 623-27-8 terephthalaldehyde, 
• 935-14-8 1,4-diethynylbenzene 
• 4843-45-2 3,3′-(1,4-phenylene)dipropiolic acid 
• 77295-67-1 1,4-bis(2,2-dibromoethenyl)benzene 

Downstream Products

• 305350-55-4 1,4-bis(2-(trimethylsilylethynyl)phenylethynyl)benzene 
• 305350-56-5 1,4-bis(2-ethynylphenylethynyl)benzene 
• 1352657-76-1 1,4-bis-[3-(2-bromophenyl)-3-tert-octylimino-1-propynyl]benzene 

Relevant articles and documents

Sulfilimines as Versatile Nitrene Transfer Reagents: Facile Access to Diverse Aza-Heterocycles

We herein report the unprecedented synthesis of diverse biologically important aza-heterocycles by employing sulfilimines as nitrene transfer reagents. This class of sulfur-based aza-ylides had not been successfully used for gold nitrene transfer before. This work contains an efficient generation of α-imino gold carbenes by N?S cleavage of sulfilimines. These gold carbenes undergo C?H insertion, cyclopropanation, and nucleophilic attack to form indoles (44 examples), 3-azabicyclo[3.1.0]hexan-2-imines (24 examples), and imidazoles (3 examples). Our study represents a unique gold-catalyzed reaction between alkynes and sulfur ylides, and also includes the first aza-heterocycle synthesis that proceeds by intermolecular nitrene transfer followed by cyclopropanation of the α-imino gold carbenes. Moreover, an unexpected synthesis of 4-acylquinolines (3 examples) from 2-acylphenyl sulfilimines and propargylic silyl ether derivatives by a 1,2-hydride shift onto the α-imino gold carbene and a subsequent Mukaiyama aldol cyclization was discovered.

Facile and efficient synthesis of 1-haloalkynes via DBU-mediated reaction of terminal alkynes and N-haloimides under mild conditions

Directly from terminal alkynes and with N-halosuccinimides (halo = Br and I) or N-cholorophthalimide as the halogen sources, DBU as the activator, 1-haloalkynes were prepared in good to excellent yields at room temperature. Bis(bromoalkyne) and bis(iodoal

Palladium-catalyzed bromoalkynylation of C-C double bonds: Ring-structure-dependent synthesis of 7-alkynyl norbornanes and cyclobutenyl halides

Strain versus flexibility: The palladium-catalyzed reaction of haloalkynes with norbornene derivatives leads to 7-alkynyl norbornane products (see scheme). Key to the success of this reaction is the formation of a "bridging" palladium species, which can rearrange to result in a C-7 functionalization. The ring-structure-dependent [2+2] cycloaddition of haloalkynes with cyclooctene has been achieved in moderate to good yields under similar conditions. Copyright