651321-53-8

Basic information

• Product Name: Benzyl-[(E)-hepta-4,6-dien-(E)-ylidene]-amine
• Synonyms: Benzyl-[(E)-hepta-4,6-dien-(E)-ylidene]-amine
• CAS NO: 651321-53-8
• Molecular Weight: 199.296
• Mol File: 651321-53-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzyl-[(E)-hepta-4,6-dien-(E)-ylidene]-amine(CAS DataBase Reference)
• NIST Chemistry Reference: Benzyl-[(E)-hepta-4,6-dien-(E)-ylidene]-amine(651321-53-8)
• EPA Substance Registry System: Benzyl-[(E)-hepta-4,6-dien-(E)-ylidene]-amine(651321-53-8)

Safety Data

• Hazardous Substances Data: 651321-53-8(Hazardous Substances Data)

Upstream product

• 33741-15-0 methyl (4E)-hepta-4,6-dienoate 
• 71779-51-6 ethyl hepta-4(E),6-dienoate 
• 79280-39-0 (4E)-hepta-4,6-dienal 
• 100-46-9 benzylamine 

Downstream Products

• 445398-78-7 N-benzyl-hepta-4(E),6-dien-1-amine 
• 194726-46-0 (3R)-3-formylpiperidine-1-carboxylic acid tert-butyl ester 
• 116574-71-1 tert-butyl (3R)-3-(hydroxymethyl)piperidine-1-carboxylate 

Relevant articles and documents

Palladium-catalyzed ring-closing reaction via C-N bond metathesis for rapid construction of saturated N-heterocycles

The ring-closing reactions based on chemical bond metathesis enable the efficient construction of a wide variety of cyclic systems which receive broad interest from medicinal and organic communities. However, the analogous reaction with C-N bond metathesis as a strategic fundamental step remains an unanswered challenge. Herein, we report the design of a new fundamental metallic C-N bond metathesis reaction that enables the palladium-catalyzed ring-closing reaction of aminodienes with aminals. The reactions proceed efficiently under mild conditions and exhibit broad substrate generality and functional group compatibility, leading to a wide variety of 5- to 16-membered N-heterocycles bearing diverse frameworks and functional groups.