653-64-5

Basic information

• Product Name: 1-(5-fluoro-2-methoxyphenyl)propan-1-one
• Synonyms: 1-(5-fluoro-2-methoxyphenyl)propan-1-one
• CAS NO: 653-64-5
• Molecular Formula: C₁₀H₁₁FO₂
• Molecular Weight: 182.1915432
• Mol File: 653-64-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(5-fluoro-2-methoxyphenyl)propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-fluoro-2-methoxyphenyl)propan-1-one(653-64-5)
• EPA Substance Registry System: 1-(5-fluoro-2-methoxyphenyl)propan-1-one(653-64-5)

Safety Data

• Hazardous Substances Data: 653-64-5(Hazardous Substances Data)

Usage

Preparation

Preparation by reaction of propionyl chloride with 4-fluoroanisole in the presence of aluminium chloride in carbon disulfide.

Upstream product

• 459-60-9 1-fluoro-4-methoxybenzene 
• 79-03-8 propionyl chloride 
• 443-09-4 1-(5-fluoro-2-hydroxyphenyl)propan-1-one 
• 74-88-4 methyl iodide 

Downstream Products

• 443-09-4 1-(5-fluoro-2-hydroxyphenyl)propan-1-one 
• 438-71-1 2-(5-fluoro-2-methoxy-phenyl)-3-methyl-quinoline-4-carboxylic acid 

Relevant articles and documents

NOVEL 5-HT2 ANTAGONISTS

The present invention relates to 1-amidino-3-aryl-2-pyrazoline derivatives of the general formula I The invention specifically relates to such derivatives which exhibit antagonizing activity towards serotonin 5-HT2B receptors. The present invention also relates to use of said compounds as a medicament and for the treatment of fibrosis, cardiovascular diseases, pain, IBD, and other inflammatory diseases, as well as pharmaceutical compositions comprising one or more of said compounds and methods of treatment.