65340-73-0 Usage
General Description
4-Amino-6-bromoquinoline is a chemical compound with the molecular formula C9H7BrN2. It is a heterocyclic aromatic compound with a quinoline backbone. This chemical is commonly used as an intermediate in organic synthesis to produce pharmaceuticals and agrochemicals. 4-Amino-6-bromoquinoline has a wide range of potential applications, including as an antimalarial, antituberculosis, and antiviral agent. It is also used in the synthesis of dyes and fluorescent probes. Additionally, it is a valuable building block for developing new materials and compounds for various industrial and research applications.
Check Digit Verification of cas no
The CAS Registry Mumber 65340-73-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,3,4 and 0 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 65340-73:
(7*6)+(6*5)+(5*3)+(4*4)+(3*0)+(2*7)+(1*3)=120
120 % 10 = 0
So 65340-73-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H7BrN2/c10-6-1-2-9-7(5-6)8(11)3-4-12-9/h1-5H,(H2,11,12)
65340-73-0Relevant articles and documents
Synthesis and evaluation of sulfonamide derivatives as potent Human Uric Acid Transporter 1 (hURAT1) inhibitors
Yang, Xintuo,Pang, Xuehai,Fan, Lei,Li, Xinghai,Chen, Yuanwei
supporting information, p. 1919 - 1922 (2017/04/10)
This letter presents synthesis and structure-activity relationship study of sulfonamide derivatives as inhibitors of Human Uric Acid Transporter 1 (hURAT1). Among all tested sulfonamide derivatives, compounds 9b, 16i and 19b exhibited excellent inhibition activity with IC50 value of 10, 2, and 83?nM, respectively. In addition, compounds 9b and 19b demonstrated moderate PK profile in rats.
