65405-67-6

Basic information

• Product Name: 4'methoxy-2-methylcinnamaldehyde
• Synonyms: 4'methoxy-2-methylcinnamaldehyde;2-Propenal, 3-(4-methoxyphenyl)-2-methyl-;ALPHA-METHYLPARA-METHOXYCINNAMICALDEHYDE;ALPHA-METHYL-4-METHOXYCINNAMALDEHYDE;PARA-METHOXY-METHYLCINNAMALDEHYDE;ALPHA-METHYL-PARA-METHOXYCINNAMALDEHYDE;3-(4-methoxyphenyl)-2-methyl-2-Propenal;alpha.-Methyl p-methoxy cinnamic aldehyde
• CAS NO: 65405-67-6
• Molecular Formula: C₁₁H₁₂O₂
• Molecular Weight: 176.2118
• EINECS: 265-737-4
• Mol File: 65405-67-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 108 °C(Press: 0.1 Torr)
• Appearance: /
• Density: 1.1265 g/cm3
• CAS DataBase Reference: 4'methoxy-2-methylcinnamaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4'methoxy-2-methylcinnamaldehyde(65405-67-6)
• EPA Substance Registry System: 4'methoxy-2-methylcinnamaldehyde(65405-67-6)

Safety Data

• Hazardous Substances Data: 65405-67-6(Hazardous Substances Data)

Usage

Description

May be prepared by formulation of the corresponding olefin.

Preparation

By formylation of the corresponding olefin.

Upstream product

• 139711-01-6 (Z)-3-(4-Methoxy-phenyl)-2-methyl-prop-2-en-1-ol 
• 100-66-3 methoxybenzene 
• 78-84-2 isobutyraldehyde 
• 25679-28-1 cis-Anethole 
• 68-12-2 N,N-dimethyl-formamide 
• 14674-38-5 N-(4-methoxybenzylidene)-p-toluenesulfonamide 
• 107-18-6 allyl alcohol 
• 139711-00-5 1-(4-methoxyphenyl)-2-methyl-2-propen-1-ol 
• 139710-95-5 1-(p-methoxyphenyl)-1,2-dibromo-2-methylpropane 
• 877-99-6 1-methoxy-4-(2-methyl-1-propenyl)benzene 
• 123-11-5 4-methoxy-benzaldehyde 
• 123-38-6 propionaldehyde 
• 4180-23-8 E-1-(4'-methoxyphenyl)prop-1-ene 

Downstream Products

• 105157-59-3 3t-(4-methoxy-phenyl)-2-methyl-acrylaldehyde-oxime 
• 1098056-14-4 3-hydroxy-1-(4-methoxyphenyl)-2-methylpent-1-ene 
• 1010821-08-5 trifluoromethanesulfonic acid 3-(4-methoxyphenyl)-2-methylhexa-1,5-dienyl ester 
• 1449584-19-3 2-(4-methoxyphenyl)-3-methyl-7,7-diphenyl-7,8-dihydropyrano[4,3-b]pyran-5(2H)-one 
• 1491165-72-0 C₂₂H₁₉ClO₄ 
• 1491165-76-4 C₂₃H₂₂O₅ 
• 1491165-71-9 C₂₂H₁₉FO₄ 
• 1491165-78-6 C₂₄H₂₄O₆ 
• 1491166-55-2 C₁₇H₁₈O₃ 
• 1491166-58-5 C₂₃H₂₂O₃ 
• 1564277-26-4 2-(4-methoxyphenyl)-3-methyl-1-(phenylamino)-1,2,7,8-tetrahydroquinolin-5(6H)-one 
• 1564277-31-1 N-(2-(4-methoxyphenyl)-3-methyl-5-oxo-5,6,7,8-tetrahydroquinolin-1(2H)-yl)benzamide 

Relevant articles and documents

Preparation method for cinnamaldehyde and derivatives thereof

The invention belongs to the technical field of organic synthesis, and particularly relates to a preparation method for cinnamaldehyde and derivatives thereof. The preparation method includes taking styrene or derivatives thereof as a substrate, reacting the substrate with a formamide solvent, iodoform and alkali at a certain temperature and under the protection of argon, and completing carbonylation to generate target products, namely the cinnamaldehyde and the derivatives thereof. The preparation method of the cinnamaldehyde and the derivatives thereof has the advantages of low cost and easyavailability of raw materials, no metal catalysis, environmental friendliness, high reaction yield and the like, thereby having a good industrial application prospect.

Poly(phosphoric acid) (PPA)-Promoted 5- exo -Cyclization of Iminium Ions Generated in Situ: A Facile Access to Functionalized Indene Derivatives

A metal-free Bronsted acid promoted two-component reaction between cinnamaldehydes and sulfonamides is described. This cascade process provides a simple and atom-economical alternative synthesis of a range of functionalized indenes from easily available starting materials. The resulting N -indenylsulfonamides were readily converted into the corresponding indenylenamines or indanones.

Use of n-substituted (3,6-dihydro)-2h-1,2-oxazine derivatives as selective mglur1 antagonists

STR1Use of a compound of formula (I) in which, R 1, R 2 and R 3 are independently hydrogen, (C 1 -C 6)alkyl, (C 2 -C 6)alkenyl, C 3 -C 10)cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted aryl(C 1 -C 6)alkyl, unsubstituted or substituted aryl(C 2 -C 6)alkenyl, halo, carboxy, (C 1 -C 6)alkoxycarbonyl or --(CH 2) m --OH wherein m is 1, 2 or 3; - - - indicates a single or a double bond; X and each independently hydrogen, or X and Y together represent a bridge of the formula --CH 2) m --, where n is 1 or 2; A 1 and A 2 are each independently an unsubstituted or substituted aryl; Z is --CO--, --SO 2 -- or --CH 2 ; provided that, when Z is --CO--, A 1 is not 3,4,5-trimethoxyphenyl; or a pharmaceutically-acceptable salt or ester thereof, for the manufacture of a medicament for the treatment of a condition indicating the administration of a selective mGluR1 antagonist.