654083-32-6

Basic information

• Product Name: Benzoic acid, 4-methoxy-, 2-acetyl-3,4,5,6-tetramethoxyphenyl ester
• CAS NO: 654083-32-6
• Molecular Formula: C20H22O8
• Molecular Weight: 390.39
• Mol File: 654083-32-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-methoxy-, 2-acetyl-3,4,5,6-tetramethoxyphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-methoxy-, 2-acetyl-3,4,5,6-tetramethoxyphenyl ester(654083-32-6)
• EPA Substance Registry System: Benzoic acid, 4-methoxy-, 2-acetyl-3,4,5,6-tetramethoxyphenyl ester(654083-32-6)

Safety Data

• Hazardous Substances Data: 654083-32-6(Hazardous Substances Data)

Upstream product

• 3162-28-5 2-hydroxy-3,4,5,6-tetramethoxyacetophenone 
• 100-07-2 4-methoxy-benzoyl chloride 

Downstream Products

• 481-53-8 tangeritin 
• 111497-80-4 1-(2-hydroxy-3,4,5,6-tetramethoxyphenyl)-3-(4-methoxyphenyl)-1,3-propanedione 

Relevant articles and documents

Improved, rapid and efficient synthesis of polymethoxyflavones under microwave irradiation and their inhibitory effects on melanogenesis

The microwave-assisted methylation of 2,5-dihydroxy-1,3-dimethoxybenzene with (CH3O)2SO2 for 5 min gave easily 1,2,3,5-tetramethoxybenzene, which was converted into pentamethoxybenzene. The microwave-assisted Friedel-Crafts acylation of pentamethoxybenzene in the presence of In(CF3SO3)3 gave pentamethoxyacetophenone for 15 min under solvent-free conditions in high yield. The microwave-assisted cyclization reaction of the diketones, which were synthesized from the acetophenone via three steps under microwave irradiation, gave the desired polymethoxyflavones for 1.5-3 min in high yields. The polymethoxyflavones showed inhibitory effects on melanogenesis in a human melanoma.