6554-21-8

Basic information

• Product Name: 3'-O-Acetyladenosine
• Synonyms: 3'-O-Acetyladenosine;Adenosine 3'-acetate
• CAS NO: 6554-21-8
• Molecular Formula: C12H15 N5 O5
• Molecular Weight: 351.4388
• Mol File: 6554-21-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 533.8°Cat760mmHg
• Flash Point: 276.6°C
• Appearance: /
• Density: 1.149g/cm³
• Vapor Pressure: 1.8E-11mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: 3'-O-Acetyladenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-O-Acetyladenosine(6554-21-8)
• EPA Substance Registry System: 3'-O-Acetyladenosine(6554-21-8)

Safety Data

• Hazardous Substances Data: 6554-21-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C22H25NO3/c1-17-7-5-6-10-20(17)22(25)26-16-21(24)23-13-11-19(12-14-23)15-18-8-3-2-4-9-18/h2-10,19H,11-16H2,1H3

Upstream product

• 18048-85-6 5'-O-(triphenylmethyl)adenosine 
• 108-24-7 acetic anhydride 
• 58-61-7 adenosine 
• 21160-02-1 benzophenone O-acetyl oxime 
• 108-05-4 vinyl acetate 
• 26594-44-5 N,O-diacetyl-4-stilbenylhydroxylamine 

Relevant articles and documents

MONOMER FOR SYNTHESIS OF RNA, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING RNA

The objective of the present invention is to provide a monomer for RNA synthesis which can be efficiently produced and therefore by which the producing cost of RNA can be remarkably decreased, and a method for efficiently producing the monomer in a small number of steps. In addition, the objective of the present invention is also to provide a method by which RNA can be efficiently produced even when a approximately stoichiometry amount of the monomer for RNA synthesis is used. The monomer for RNA synthesis according to the present invention is represented by the following formula (I) or (I'): wherein R1 is a protective group of the hydroxy group and R2 is an alkyl group or the like.

The action of adenosine deaminase (E.C. 3.5.4.4.) on adenosine and deoxyadenosine acetates: The crucial role of the 5'-hydroxy group for the enzyme activity

From adenosine 1, 2'-deoxyadenosine 3 and 3'-deoxyadenosine 5 all the acetates were prepared by lipase-catalyzed reactions. Only the acetates with free 5'-hydroxy group were deaminated by adenosine deaminase (ADA), confirming the crucial role of 5'-OH for the enzyme activity. (C) 2000 Elsevier Science Ltd.

A specific colorimetric and cytochemical substrate for ribonuclease T 2 : adenosine-3'-( -naphtylphosphate).

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