65555-88-6Relevant articles and documents
Chiral azo compounds: Enantioselective synthesis and transformations into β-amino alcohols and α-amino acids with a quaternary stereocenter
Dietz, Friedrich R.,Prechter, Agnes,Gr?ger, Harald,Heinrich, Markus R.
, p. 655 - 657 (2011/03/21)
Taking advantage of radical carboaminations producing azo compounds, a new chemo-enzymatic approach to enantiomerically enriched azo alcohols, β-amino alcohols and non-natural (aromatic) amino acids with a quaternary stereocenter is reported.
Synthesis of Optically Pure α-Alkylated α-Amino Acids and a Single-Step Method for Enatiomeric Excess Determination
Kruizinga, Wim H.,Bolster, John,Kellogg, Richard M.,Kamphuis, Johan,Boesten, Wilhelmus H. J.,et al.
, p. 1826 - 1827 (2007/10/02)
A method for the enzymatic resolution of the amides of some racemic α-alkylated amino acids is described as well as a method involving derivatization with (S)-2-chloropropionyl chloride followed by 1H NMR analysis to establish the enantiomeric excesses of the free amino acids.
Chirally substituted 2-imidazolin-5-ones
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, (2008/06/13)
Chirally substituted 2-imidazolin-5-ones and their use as intermediates for the preparation of optically active aminoacids, especially of optically active α-substituted aminoacids.