656-57-5

Basic information

• Product Name: 1-BROMO-2-FLUOROCYCLOHEXANE
• Synonyms: 1-BROMO-2-FLUOROCYCLOHEXANE;1-BROMO-FLUOROCYCLOHEXANE;1β-Fluoro-2α-bromocyclohexane
• CAS NO: 656-57-5
• Molecular Formula: C₆H₁₀BrF
• Molecular Weight: 181.05
• Mol File: 656-57-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 74.5-76.5/19mm
• Flash Point: 56.8 ºC
• Appearance: /
• Density: 1.46
• Refractive Index: 1.4800 and le 1.4840
• CAS DataBase Reference: 1-BROMO-2-FLUOROCYCLOHEXANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-2-FLUOROCYCLOHEXANE(656-57-5)
• EPA Substance Registry System: 1-BROMO-2-FLUOROCYCLOHEXANE(656-57-5)

Safety Data

• Hazard Codes: F,Xn
• Statements: 22-36
• HazardClass: FLAMMABLE
• Hazardous Substances Data: 656-57-5(Hazardous Substances Data)

Usage

General Description

1-Bromo-2-fluorocyclohexane is a synthetic, organic chemical compound, part of the family of Halocyclohexanes. The molecular formula for this compound is C6H10BrF. It carries two halogen atoms, bromine and fluorine, hence the prefix "Bromo" and "Fluoro" in its name. Its structure is composed of a six-membered carbon ring (cyclohexane) with bromine and fluorine atoms attached to the carbon at positions 1 and 2 respectively. Known for its ability to undergo multiple chemical reactions, it is often used in research and development within the chemistry field. However, like many halogenated organic compounds, it should be handled with care due to potential risk and reactivity. Specific handling and safety details should be referenced on its Material Safety Data Sheet (MSDS).

Upstream product

• 110-83-8 cyclohexene 

Downstream Products

• 1461-23-0 tributyltin bromide 

Relevant articles and documents

Improved and facile addition reactions of pentafluorosulfanyl bromide

A solution of SF5Br in CCl3F (0.5-1 M) was utilized to effect the addition of pentafluorosulfanyl bromide (SF5Br) to olefins. The reaction of the SF5Br solution in the presence of triethylborane (0.1 equiv) with an olefin over 20 min at 0 °C gave pentafluorosulfanylated compound 2(a-f) in high yield (Table 2). An efficient route for the preparation of synthetically useful SF5-containing esters is also described.

Stable dialkyl ether/poly(hydrogen fluoride) complexes: Dimethyl ether/poly(hydrogen fluoride), a new, convenient, and effective fluorinating agent

The preparation, 1H, 13C, and 19F NMR structural characterization as well as with DFT-based theoretical calculations of stable dialkyl ether/poly(hydrogen fluoride) complexes are reported. Dimethyl ether/poly(hydrogen fluoride) (DMEPHF), are stable complexes of particular interest and use. The DFT calculations, that are in agreement with NMR data, suggest a cyclic poly(hydrogen fluoride) bridged structure for DMEPHF. The complex, DME-5 HF was found to be a convenient and effective new fluorinating agent with the ease. of workup and applied to several fluorination reactions, such as the hydrofluorination and bromofluorination of alkenes, and fluorination of alcohols giving good to excellent yield with high selectivity. Homologous dialkyl ether/poly(hydrogen fluoride) (R2O/[HF]n R = Et, nPr) systems are also stable and suitable for fluorination reactions.

Silver Fluoride Supported on Calcium Fluoride. Improved Fluorination and Halofluorination Reactions

Silver fluoride dispersed on the surface of calcium fluoride shows improved fluoride nucleophilicity for halogen exchange and addition to alkenes.