65671-53-6 Usage
Description
BOC-LYS(ME)2-OH, also known as N-(tert-butoxycarbonyl)-N,N-dimethyl-L-lysine, is a synthetic amino acid derivative with a protected side chain. It is characterized by the presence of a tert-butoxycarbonyl (BOC) group and two methyl (Me) groups on the side chain, which provide stability and reactivity in various chemical reactions.
Uses
Used in Pharmaceutical Industry:
BOC-LYS(ME)2-OH is used as a key intermediate in the synthesis of peptidyl α-keto thiazoles, which serve as tissue factor VIIa inhibitors. These inhibitors play a crucial role in the development of therapeutic agents for the treatment of coagulation disorders and related conditions.
Additionally, BOC-LYS(ME)2-OH is utilized in the preparation of tetrahydropyranylglycine sulfonamides, which act as bradykinin hB2 receptor antagonists. These antagonists are valuable in the research and development of drugs targeting the bradykinin pathway, which is involved in various physiological processes, including pain, inflammation, and blood pressure regulation.
Check Digit Verification of cas no
The CAS Registry Mumber 65671-53-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,6,7 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 65671-53:
(7*6)+(6*5)+(5*6)+(4*7)+(3*1)+(2*5)+(1*3)=146
146 % 10 = 6
So 65671-53-6 is a valid CAS Registry Number.
65671-53-6Relevant articles and documents
ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION OF BRM AND METHODS THEREOF
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Page/Page column 224, (2022/02/05)
The subject matter described herein is directed to antibody-CIDE conjugates (Ab-CIDEs) that target BRM for degradation, to pharmaceutical compositions containing them, and to their use in treating diseases and conditions where BRM degradation is beneficial.
Development of a fluorogenic probe with a transesterification switch for detection of histone deacetylase activity
Baba, Reisuke,Hori, Yuichiro,Mizukami, Shin,Kikuchi, Kazuya
supporting information, p. 14310 - 14313 (2012/11/07)
Histone deacetylases (HDACs) are key enzymatic regulators of many cellular processes such as gene expression, cell cycle, and tumorigenesis. These enzymes are attractive targets for drug development. However, very few simple methods for monitoring HDAC ac