65674-14-8

Basic information

• Product Name: 1,2-dibromo-4-phenylbutane
• Synonyms: 1,2-dibromo-4-phenylbutane
• CAS NO: 65674-14-8
• Molecular Weight: 292.013
• Mol File: 65674-14-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1,2-dibromo-4-phenylbutane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dibromo-4-phenylbutane(65674-14-8)
• EPA Substance Registry System: 1,2-dibromo-4-phenylbutane(65674-14-8)

Safety Data

• Hazardous Substances Data: 65674-14-8(Hazardous Substances Data)

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 768-56-9 4-Phenylbut-1-ene 
• 1126-76-7 1,2-Epoxy-4-phenylbutane 
• 767-99-7 2-phenylbut-2-ene 

Downstream Products

• 16520-62-0 4-Phenyl-1-butyne 
• 62692-41-5 (4-bromobut-3-en-1-yl)benzene 
• 62692-40-4 (3-bromobut-3-en-1-yl)benzene 
• 62692-41-5 (Z)-(4-bromobut-3-en-1-yl)benzene 
• 62692-41-5 (E)-(4-bromobut-3-en-1-yl) benzene 
• 105535-08-8 1-(3,4-dibromobutyl)-2-nitrobenzene 

Relevant articles and documents

Copper and Zinc Copromoted Bromo(chloro)trifluoromethylation of Alkenes and Alkynes with Trifluoromethanesulfonic Anhydride

The first copper and zinc copromoted trifluoromethylation using trifluoromethanesulfonic anhydride (Tf2O) as a trifluoromethylating reagent has been developed. The reaction of alkenes or alkynes with Tf2O in the presence of CuX2 (X = Br, Cl), Zn powder, and 2,2′-bipyridine affords bromo(chloro)trifluoromethylated products in good yields. CuX2 plays a dual role as the catalyst and halide source, whereas 2,2′-bipyridine acts as both the activation reagent and ligand.

One-Pot Strategy for Thiazoline Synthesis from Alkenes and Thioamides

A convenient synthesis of a privileged pharmaceutical motif, thiazoline is accomplished. This reaction utilizes simple and readily available alkene and thioamide substrates in an intermolecular fashion via a simple one-pot procedure. A wide range of functional groups is tolerated, and the thiazoline product has been further utilized for the synthesis of the corresponding β-aminothiol and thiazole from routine hydrolysis and oxidation protocols.

Efficient bromination of olefins, alkynes, and ketones with dimethyl sulfoxide and hydrobromic acid

The oxidative bromination of olefins, alkynes, and ketones has been developed with HBr as the brominating reagent and DMSO as the mild oxidant. The simple conditions, high bromide-atom-economy, as well as easy accessibility and low cost of DMSO and HBr make the present strategy prospective for the synthesis of dibrominated alkanes, dibrominated alkenes and α-bromoketones.