65686-77-3 Usage
General Description
2,2,2-TRIFLUORO-1-(4-METHOXY-PHENYL)-ETHYLAMINE HYDROCHLORIDE is a chemical compound with the molecular formula C9H12F3NO. It is a white crystalline solid that is commonly used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. 2,2,2-TRIFLUORO-1-(4-METHOXY-PHENYL)-ETHYLAMINE HYDROCHLORIDE plays a crucial role in the production of medicines that are used to treat a wide range of conditions, including psychiatric disorders and neurological diseases. Additionally, it is also utilized in the field of organic chemistry for its reactivity and ability to participate in various chemical reactions. The hydrochloride form of this compound is commonly used in research and industrial applications due to its stability and ease of handling. Overall, 2,2,2-TRIFLUORO-1-(4-METHOXY-PHENYL)-ETHYLAMINE HYDROCHLORIDE is an important and versatile chemical compound with various valuable applications in the pharmaceutical and chemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 65686-77-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,6,8 and 6 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 65686-77:
(7*6)+(6*5)+(5*6)+(4*8)+(3*6)+(2*7)+(1*7)=173
173 % 10 = 3
So 65686-77-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H10F3NO.ClH/c1-14-7-4-2-6(3-5-7)8(13)9(10,11)12;/h2-5,8H,13H2,1H3;1H
65686-77-3Relevant articles and documents
Thermocontrolled benzylimine-benzaldimine rearrangement over Nafion-H catalysts for efficient entry into α-trifluoromethylbenzylamines
Prakash, G.K. Surya,Glinton, Kevin E.,Panja, Chiradeep,Gurung, Laxman,Battamack, Patrice T.,T?r?k, Béla,Mathew, Thomas,Olah, George A.
experimental part, p. 607 - 611 (2012/02/13)
Nafion-H and Nafion SAC-13 are efficient solid Br?nsted acid catalysts for the preparation of trifluoromethyl ketimines from benzylamines and trifluoromethylated ketones in high yields. A finely tuned benzylimine- benzaldimine rearrangement by facile 1,3-hydrogen shift has been achieved for the formation of fluorinated benzaldimines in high yields by careful optimization of reaction conditions including attempts under microwave conditions and a flow system. These α-trifluoromethylated benzaldimines are efficient precursors for pharmaceutically important α- trifluoromethylated benzylamines, accessed through their direct acid hydrolysis.
