65715-09-5

Basic information

• Product Name: 1,3,4-Oxadiazole-2(3H)-thione, 3-benzoyl-5-phenyl-
• CAS NO: 65715-09-5
• Molecular Formula: C15H10N2O2S
• Molecular Weight: 282.323
• Mol File: 65715-09-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,3,4-Oxadiazole-2(3H)-thione, 3-benzoyl-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4-Oxadiazole-2(3H)-thione, 3-benzoyl-5-phenyl-(65715-09-5)
• EPA Substance Registry System: 1,3,4-Oxadiazole-2(3H)-thione, 3-benzoyl-5-phenyl-(65715-09-5)

Safety Data

• Hazardous Substances Data: 65715-09-5(Hazardous Substances Data)

Upstream product

• 65-85-0 benzoic acid 
• 122350-19-0 3,3'-carbonylbis<5-phenyl-1,3,4-oxadiazole-2(3H)-thione> 
• 3004-42-0 5-phenyl-1,3,4-oxadiazole-2(3H)-thione 
• 98-88-4 benzoyl chloride 
• 17473-79-9 1-benzoyl-2-tert-butylhydrazine 
• 463-71-8 thiophosgene 
• 112225-87-3 benzoic acid N'-benzoyl-N-tert-butylhydrazide 
• 75-15-0 carbon disulfide 
• 613-94-5 benzoic acid hydrazide 

Downstream Products

• 93-99-2 benzoic acid phenyl ester 
• 93-98-1 N-phenyl benzoyl amide 
• 884-09-3 phenyl thiobenzoate 

Relevant articles and documents

A novel convenient synthesis of 1,3,4-oxadiazol-2-ones and -thiones from N-tert-butyldiacylhydrazines

An attractive, novel, convenient process for the preparation of 3,5-disubstituted-3H-[1,3,4]-oxadiazol-2-ones and -thiones from the reaction of various equivalent and non-equivalent N-tertbutyldiacylhydrazines with potassium tert-butoxide followed by treatment with phosgene or thiophosgene, respectively, has been discovered. The 3,5-disubstituted-3H-[1,3,4]-oxadiazol-2-ones and -thiones are confirmed both analytically and chemically. Various equivalent and non-equivalent N-tert-butyldiacylhydrazines are conveniently synthesized from the reaction of tert-butylhydrazine hydrochloride in the presence of i-Pr2NEt, with acid chloride #1 followed by subsequent treatment with acid chloride #2. Both the syntheses of 3,5-disubstituted-3H-[1,3,4]-oxadiazol-2-ones and -thiones, as well as N-tert-butyldiacylhydrazines, are easily performed on multigram scales.