65819-31-0Relevant articles and documents
A Reinvestigation of the Preparation, Properties, and Applications of Aminomethyl and 4-Methylbenzhydrylamin
Howard Adams,Cook, Ronald M.,Hudson, Derek,Jammalamadaka, Vasu,Lyttle, Matthew H.,Songster, Michael F.
, p. 3706 - 3716 (2007/10/03)
Mild, efficient conditions have been developed for the preparation of 4-methylbenzhydrylamine polystyrene (MBHA) and aminomethyl polystyrene (AMPS) resins by a two-step procedure with synthons 1a and 1c. The products possess excellent swelling characteristics and acylate readily with linkers yielding useful derivatives, which retain good swelling and reactivity. Comparative studies with these resins, and their poly(ethylene glycol) (PEG) derivatives, yield insights into the role of spacer arm and environment effects in synthesis facilitation.