659745-39-8

Basic information

• Product Name: Benzamide, N-[2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl]-4-(trifluoromethyl)-
• CAS NO: 659745-39-8
• Molecular Formula: C16H11ClF6N2O
• Molecular Weight: 396.72
• Mol File: 659745-39-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzamide, N-[2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl]-4-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-[2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl]-4-(trifluoromethyl)-(659745-39-8)
• EPA Substance Registry System: Benzamide, N-[2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl]-4-(trifluoromethyl)-(659745-39-8)

Safety Data

• Hazardous Substances Data: 659745-39-8(Hazardous Substances Data)

Upstream product

• 75806-84-7 2-bromo-3-chloro-5-(trifluoromethyl)pyridine 
• 329-15-7 4-trifluoromethyl-phenyl acetyl chloride 

Relevant articles and documents

Catalytic Strategy for Regioselective Arylethylamine Synthesis

A mild, modular, and practical catalytic system for the synthesis of the highly privileged phenethylamine pharmacophore is reported. Using a unique combination of organic catalysts to promote the transfer of electrons and hydrogen atoms, this system performs direct hydroarylation of vinyl amine derivatives with a wide range of aryl halides (including aryl chlorides). This general and highly chemoselective protocol delivers a broad range of arylethylamine products with complete regiocontrol. The utility of this process is highlighted by its scalability and the modular synthesis of an array of bioactive small molecules.