65990-86-5 Usage
General Description
2,2,2-TRIFLUORO-1-(4-CHLORO-PHENYL)-ETHYLAMINE HYDROCHLORIDE is a chemical compound that consists of a 2,2,2-trifluoroethylamine molecule with a hydrochloride group attached. The compound has a molecular formula of C8H9ClF3N, with a molar mass of 211.61 g/mol. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, and also as a building block in the preparation of other chemical compounds. The compound is a white to light yellow solid at room temperature and is typically handled and stored in a cool, dry, and well-ventilated area. It is important to handle this chemical with care and follow proper safety protocols when working with it in a laboratory setting.
Check Digit Verification of cas no
The CAS Registry Mumber 65990-86-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,9,9 and 0 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 65990-86:
(7*6)+(6*5)+(5*9)+(4*9)+(3*0)+(2*8)+(1*6)=175
175 % 10 = 5
So 65990-86-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H7ClF3N.ClH/c9-6-3-1-5(2-4-6)7(13)8(10,11)12;/h1-4,7H,13H2;1H
65990-86-5Relevant articles and documents
Thermocontrolled benzylimine-benzaldimine rearrangement over Nafion-H catalysts for efficient entry into α-trifluoromethylbenzylamines
Prakash, G.K. Surya,Glinton, Kevin E.,Panja, Chiradeep,Gurung, Laxman,Battamack, Patrice T.,T?r?k, Béla,Mathew, Thomas,Olah, George A.
, p. 607 - 611 (2012/02/13)
Nafion-H and Nafion SAC-13 are efficient solid Br?nsted acid catalysts for the preparation of trifluoromethyl ketimines from benzylamines and trifluoromethylated ketones in high yields. A finely tuned benzylimine- benzaldimine rearrangement by facile 1,3-hydrogen shift has been achieved for the formation of fluorinated benzaldimines in high yields by careful optimization of reaction conditions including attempts under microwave conditions and a flow system. These α-trifluoromethylated benzaldimines are efficient precursors for pharmaceutically important α- trifluoromethylated benzylamines, accessed through their direct acid hydrolysis.
