66012-26-8

Basic information

• Product Name: L-Tyrosine, N-[(phenylmethoxy)carbonyl]glycyl-, methyl ester
• CAS NO: 66012-26-8
• Molecular Formula: C20H22N2O6
• Molecular Weight: 386.404
• Mol File: 66012-26-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: L-Tyrosine, N-[(phenylmethoxy)carbonyl]glycyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Tyrosine, N-[(phenylmethoxy)carbonyl]glycyl-, methyl ester(66012-26-8)
• EPA Substance Registry System: L-Tyrosine, N-[(phenylmethoxy)carbonyl]glycyl-, methyl ester(66012-26-8)

Safety Data

• Hazardous Substances Data: 66012-26-8(Hazardous Substances Data)

Upstream product

• 1080-06-4 L-Tyr-OMe 
• 80681-01-2 [2-Oxo-2-(2-thioxo-thiazolidin-3-yl)-ethyl]-carbamic acid benzyl ester 
• 35264-84-7 ZGly, triethylammonium salt 
• 1080-06-4 L-Tyr-OCH₃ 
• 67-56-1 methanol 
• 19790-44-4 Cbz-Gly-Tyr-NH₂ 
• 16707-70-3 2-(((benzyloxy)carbonyl)amino)ethanethioic S-acid 
• 3417-91-2 L-tyrosine methyl ester HCl 
• 1330059-26-1 N-benzyloxycarbonylglycine 9-fluorenylmethyl thioester 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 

Downstream Products

• 7801-35-6 Cbz-G-Y-OH 
• 122411-87-4 {2-[(S)-2-(2-Benzyloxycarbonylamino-acetylamino)-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetic acid 
• 184713-88-0 Z-Gly-Tyr-Gly-GlyOEt 
• 193625-89-7 H-Gly-Tyr-Gly-Gly-Pro-Phe-Pro-OH 
• 193625-90-0 Z-Gly-Tyr-Gly-Gly-Pro-Phe-Pro-OBz 
• 934840-98-9 C₂₈H₃₀N₄O₆ 
• 193274-60-1 (S)-3-(4-Methoxymethoxy-benzyl)-piperazine-2,5-dione 

Relevant articles and documents

PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITORS AS diAGNOSTIC AND RAdiONUCLIDE THERAPEUTIC AGENTS

The present disclosure relates to compounds according to Formula I. These compounds display very good binding affinities to the PSMA binding sites. They comprise a radioactive isotope or a chelating moiety that can be labeled with a radioactive metal such as [68Ga]or [177Lu]. The present disclosure also relates to pharmaceutical compositions comprising a pharmaceutical acceptable carrier and a compound of Formula I or a complex thereof, or a pharmaceutically acceptable salt thereof.

Processes for forming amide bonds and compositions related thereto

The disclosure relates to methods for producing amide bonds and reagents related thereto. In some embodiments, the disclosure relates to methods of producing an amide comprising mixing an O-silylated thionoester and an amine under conditions such that an amide is formed. In another embodiment, the disclosure relates to mixing a thiolacid, a silylating agent, and an amine under conditions such that an amide is formed.

Application of an organophosphorus reagent depbt for synthesis of cycloheptapeptide

A cycloheptapeptide cyclo(Gly-Tyr-Gly-Gly-Pro-Phe-Pro), which was isolated and identified from one kind of Chinese medicinal herbs, was chosen as a model cyclopeptide, to evaluate an organophosphorus reagent, 3-(diethyloxyphosphoryloxy)-1,2,3-benzotriazin